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- W2012442571 abstract "Ethanol decreased the activity of carnitine palmitoyltransferase I and the rate of fatty acid oxidation in rat hepatocytes in short-term incubations. These effects were mimicked by acetaldehyde, the product of hepatic ethanol metabolism, and were absent when ethanol oxidation was prevented by 4-methylpyrazole. Ethanol was also able to increase intracellular malonyl-CoA levels. The results suggest that inhibition of fatty acid translocation into mitochondria may play an important role in the ethanol-induced inhibition of hepatic fatty acid oxidation." @default.
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- W2012442571 date "1988-07-01" @default.
- W2012442571 modified "2023-10-02" @default.
- W2012442571 title "Short-term inhibition of carnitine palmitoyltransferase I activity in rat hepatocytes incubated with ethanol" @default.
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- W2012442571 doi "https://doi.org/10.1016/0006-291x(88)90193-3" @default.
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