FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012470011> ?p ?o ?g. }

• W2012470011 endingPage "e2793" @default.
• W2012470011 startingPage "e2793" @default.
• W2012470011 abstract "PlcR is a Bacillus cereus transcriptional regulator, which activates gene expression by binding to a nucleotidic sequence called the 'PlcR box'. To build a list of all genes included in the PlcR regulon, a consensus sequence was identified by directed mutagenesis. The reference strain ATCC14579 sequenced genome was searched for occurrences of this consensus sequence to produce a virtual regulon. PlcR control of these genes was confirmed by comparing gene expression in the reference strain and its isogenic Delta-plcR strain using DNA microarrays, lacZ fusions and proteomics methods. The resulting list included 45 genes controlled by 28 PlcR boxes. Forty of the PlcR controlled proteins were exported, of which 22 were secreted in the extracellular medium and 18 were bound or attached to cell wall structures (membrane or peptidoglycan layer). The functions of these proteins were related to food supply (phospholipases, proteases, toxins), cell protection (bacteriocins, toxins, transporters, cell wall biogenesis) and environment-sensing (two-component sensors, chemotaxis proteins, GGDEF family regulators). Four genes coded for cytoplasmic regulators. The PlcR regulon appears to integrate a large range of environmental signals, including food deprivation and self cell-density, and regulate the transcription of genes designed to overcome obstacles that hinder B. cereus growth within the host: food supply, host barriers, host immune defenses, and competition with other bacterial species. PlcR appears to be a key component in the efficient adaptation of B. cereus to its host environment." @default.
• W2012470011 created "2016-06-24" @default.
• W2012470011 creator A5064030144 @default.
• W2012470011 creator A5066276934 @default.
• W2012470011 creator A5074001089 @default.
• W2012470011 creator A5079316574 @default.
• W2012470011 creator A5081938031 @default.
• W2012470011 creator A5082599890 @default.
• W2012470011 creator A5088848983 @default.
• W2012470011 creator A5089088890 @default.
• W2012470011 date "2008-07-30" @default.
• W2012470011 modified "2023-10-11" @default.
• W2012470011 title "The PlcR Virulence Regulon of Bacillus cereus" @default.
• W2012470011 cites W1569357121 @default.
• W2012470011 cites W1963563104 @default.
• W2012470011 cites W1967048177 @default.
• W2012470011 cites W1981563187 @default.
• W2012470011 cites W1985114552 @default.
• W2012470011 cites W1985185645 @default.
• W2012470011 cites W1993641741 @default.
• W2012470011 cites W1995782802 @default.
• W2012470011 cites W2013444425 @default.
• W2012470011 cites W2014917430 @default.
• W2012470011 cites W2020027019 @default.
• W2012470011 cites W2022527211 @default.
• W2012470011 cites W2036874847 @default.
• W2012470011 cites W2038679047 @default.
• W2012470011 cites W2041877620 @default.
• W2012470011 cites W2046225429 @default.
• W2012470011 cites W2047005829 @default.
• W2012470011 cites W2050523158 @default.
• W2012470011 cites W2053895598 @default.
• W2012470011 cites W2069068356 @default.
• W2012470011 cites W2076379463 @default.
• W2012470011 cites W2078064634 @default.
• W2012470011 cites W2081098333 @default.
• W2012470011 cites W2083604712 @default.
• W2012470011 cites W2096324489 @default.
• W2012470011 cites W2103553982 @default.
• W2012470011 cites W2109310735 @default.
• W2012470011 cites W2111310696 @default.
• W2012470011 cites W2112684036 @default.
• W2012470011 cites W2117782092 @default.
• W2012470011 cites W2117817642 @default.
• W2012470011 cites W2118292875 @default.
• W2012470011 cites W2120266240 @default.
• W2012470011 cites W2121297340 @default.
• W2012470011 cites W2122020611 @default.
• W2012470011 cites W2123284949 @default.
• W2012470011 cites W2129366833 @default.
• W2012470011 cites W2138214924 @default.
• W2012470011 cites W2140431424 @default.
• W2012470011 cites W2141631862 @default.
• W2012470011 cites W2142036182 @default.
• W2012470011 cites W2142237413 @default.
• W2012470011 cites W2149486791 @default.
• W2012470011 cites W2152105363 @default.
• W2012470011 cites W2158259454 @default.
• W2012470011 cites W2164029628 @default.
• W2012470011 cites W2166383488 @default.
• W2012470011 cites W2170450727 @default.
• W2012470011 cites W2171535756 @default.
• W2012470011 doi "https://doi.org/10.1371/journal.pone.0002793" @default.
• W2012470011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2464732" @default.
• W2012470011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18665214" @default.
• W2012470011 hasPublicationYear "2008" @default.
• W2012470011 type Work @default.
• W2012470011 sameAs 2012470011 @default.
• W2012470011 citedByCount "255" @default.
• W2012470011 countsByYear W20124700112012 @default.
• W2012470011 countsByYear W20124700112013 @default.
• W2012470011 countsByYear W20124700112014 @default.
• W2012470011 countsByYear W20124700112015 @default.
• W2012470011 countsByYear W20124700112016 @default.
• W2012470011 countsByYear W20124700112017 @default.
• W2012470011 countsByYear W20124700112018 @default.
• W2012470011 countsByYear W20124700112019 @default.
• W2012470011 countsByYear W20124700112020 @default.
• W2012470011 countsByYear W20124700112021 @default.
• W2012470011 countsByYear W20124700112022 @default.
• W2012470011 countsByYear W20124700112023 @default.
• W2012470011 crossrefType "journal-article" @default.
• W2012470011 hasAuthorship W2012470011A5064030144 @default.
• W2012470011 hasAuthorship W2012470011A5066276934 @default.
• W2012470011 hasAuthorship W2012470011A5074001089 @default.
• W2012470011 hasAuthorship W2012470011A5079316574 @default.
• W2012470011 hasAuthorship W2012470011A5081938031 @default.
• W2012470011 hasAuthorship W2012470011A5082599890 @default.
• W2012470011 hasAuthorship W2012470011A5088848983 @default.
• W2012470011 hasAuthorship W2012470011A5089088890 @default.
• W2012470011 hasBestOaLocation W20124700111 @default.
• W2012470011 hasConcept C104317684 @default.
• W2012470011 hasConcept C143065580 @default.
• W2012470011 hasConcept C165864922 @default.
• W2012470011 hasConcept C167625842 @default.
• W2012470011 hasConcept C2777118263 @default.
• W2012470011 hasConcept C2781196521 @default.
• W2012470011 hasConcept C523546767 @default.

• next