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- W2012491333 abstract "Fourteen patients with an average of more than 60 episodes of upper airway obstruction during night sleep were treated with a nonsedating tricyclic antidepressant, protriptyline. Frequency and duration of recorded apneas decreased in 11 cases, and satisfactory control of sleep apnea was maintained with medical therapy alone in 8 of these 11 patients for 7 to 15 months. Potential adverse effects of protriptyline, particularly on the cardiovascular system, limit its use in this illness. These results indicate the possibility of pharmacologic reversal of sleep-induced incoordination of the upper airway." @default.
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- W2012491333 date "1979-09-01" @default.
- W2012491333 modified "2023-09-27" @default.
- W2012491333 title "Sleep apnea: Treatment with protriptyline" @default.
- W2012491333 doi "https://doi.org/10.1212/wnl.29.9_part_1.1287" @default.
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