Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012503494> ?p ?o ?g. }
- W2012503494 endingPage "S1322" @default.
- W2012503494 startingPage "S1317" @default.
- W2012503494 abstract "To isolate compounds from K. pinnata and elucidate their structures and to explore preliminary antioxidant, antimicrobial, cytotoxic and thombolytic activities of extractives of the plant. The methanol extract of whole plant of K. pinnata has been subjected to different chromatographic separation and purification processes to isolate the secondary metabolites. The structures of the isolated compounds have been elucidated by extensive NMR studies. The free radical scavenging activity of the crude extract and its different Kupchan fractions were determined on stable radical DPPH. In vitro antimicrobial activity was determined by the disk diffusion method. Cytotoxicity screening has been performed against Artemia salina. Total phenolics content, membrane stabilizing activity and thombolytic activities were assessed by following established protocol. The isolated compounds were identified as glut-5(6)-en-3-one, taraxerone, 3β-friedelanol, β-amyrin-3-acetate, 3,5,7,3′,5′-pentahydroxyflavone and β-sitosterol. The chloroform soluble fraction showed potent antioxidant activity of (IC50= 80.0 μg/mL) and significant cytotoxicity, while the crude extract demonstrated noticeable total polyphenol content (149.24 mg of GAE/gm of extractive), moderate membrane stabilizing activity and inhibition of clot lysis of blood. The obtained results rationalize the folkloric use of the plant and can be further investigated to isolate the active compounds responsible for the biological activities." @default.
- W2012503494 created "2016-06-24" @default.
- W2012503494 creator A5019430470 @default.
- W2012503494 creator A5021356383 @default.
- W2012503494 creator A5047176690 @default.
- W2012503494 creator A5052812213 @default.
- W2012503494 creator A5070554568 @default.
- W2012503494 creator A5078953104 @default.
- W2012503494 creator A5085255814 @default.
- W2012503494 date "2012-01-01" @default.
- W2012503494 modified "2023-10-01" @default.
- W2012503494 title "Chemical and biological studies of Kalanchoe pinnata (Lam.) growing in Bangladesh" @default.
- W2012503494 cites W1937394558 @default.
- W2012503494 cites W1949686842 @default.
- W2012503494 cites W1966573672 @default.
- W2012503494 cites W1971841798 @default.
- W2012503494 cites W1984756160 @default.
- W2012503494 cites W2005626020 @default.
- W2012503494 cites W2046919174 @default.
- W2012503494 cites W2065853716 @default.
- W2012503494 cites W2077946722 @default.
- W2012503494 cites W2086563847 @default.
- W2012503494 cites W2091343206 @default.
- W2012503494 cites W2136931384 @default.
- W2012503494 cites W2169274012 @default.
- W2012503494 cites W2340668334 @default.
- W2012503494 cites W3142359411 @default.
- W2012503494 doi "https://doi.org/10.1016/s2221-1691(12)60408-0" @default.
- W2012503494 hasPublicationYear "2012" @default.
- W2012503494 type Work @default.
- W2012503494 sameAs 2012503494 @default.
- W2012503494 citedByCount "16" @default.
- W2012503494 countsByYear W20125034942014 @default.
- W2012503494 countsByYear W20125034942015 @default.
- W2012503494 countsByYear W20125034942016 @default.
- W2012503494 countsByYear W20125034942017 @default.
- W2012503494 countsByYear W20125034942018 @default.
- W2012503494 countsByYear W20125034942019 @default.
- W2012503494 countsByYear W20125034942020 @default.
- W2012503494 countsByYear W20125034942021 @default.
- W2012503494 countsByYear W20125034942023 @default.
- W2012503494 crossrefType "journal-article" @default.
- W2012503494 hasAuthorship W2012503494A5019430470 @default.
- W2012503494 hasAuthorship W2012503494A5021356383 @default.
- W2012503494 hasAuthorship W2012503494A5047176690 @default.
- W2012503494 hasAuthorship W2012503494A5052812213 @default.
- W2012503494 hasAuthorship W2012503494A5070554568 @default.
- W2012503494 hasAuthorship W2012503494A5078953104 @default.
- W2012503494 hasAuthorship W2012503494A5085255814 @default.
- W2012503494 hasConcept C109316439 @default.
- W2012503494 hasConcept C116073593 @default.
- W2012503494 hasConcept C178790620 @default.
- W2012503494 hasConcept C185592680 @default.
- W2012503494 hasConcept C202751555 @default.
- W2012503494 hasConcept C2778004101 @default.
- W2012503494 hasConcept C2779858419 @default.
- W2012503494 hasConcept C2781144210 @default.
- W2012503494 hasConcept C2781201647 @default.
- W2012503494 hasConcept C2781401929 @default.
- W2012503494 hasConcept C29730261 @default.
- W2012503494 hasConcept C31903555 @default.
- W2012503494 hasConcept C43617362 @default.
- W2012503494 hasConcept C4937899 @default.
- W2012503494 hasConcept C55493867 @default.
- W2012503494 hasConcept C556039675 @default.
- W2012503494 hasConcept C57409179 @default.
- W2012503494 hasConcept C70899900 @default.
- W2012503494 hasConcept C71924100 @default.
- W2012503494 hasConceptScore W2012503494C109316439 @default.
- W2012503494 hasConceptScore W2012503494C116073593 @default.
- W2012503494 hasConceptScore W2012503494C178790620 @default.
- W2012503494 hasConceptScore W2012503494C185592680 @default.
- W2012503494 hasConceptScore W2012503494C202751555 @default.
- W2012503494 hasConceptScore W2012503494C2778004101 @default.
- W2012503494 hasConceptScore W2012503494C2779858419 @default.
- W2012503494 hasConceptScore W2012503494C2781144210 @default.
- W2012503494 hasConceptScore W2012503494C2781201647 @default.
- W2012503494 hasConceptScore W2012503494C2781401929 @default.
- W2012503494 hasConceptScore W2012503494C29730261 @default.
- W2012503494 hasConceptScore W2012503494C31903555 @default.
- W2012503494 hasConceptScore W2012503494C43617362 @default.
- W2012503494 hasConceptScore W2012503494C4937899 @default.
- W2012503494 hasConceptScore W2012503494C55493867 @default.
- W2012503494 hasConceptScore W2012503494C556039675 @default.
- W2012503494 hasConceptScore W2012503494C57409179 @default.
- W2012503494 hasConceptScore W2012503494C70899900 @default.
- W2012503494 hasConceptScore W2012503494C71924100 @default.
- W2012503494 hasIssue "3" @default.
- W2012503494 hasLocation W20125034941 @default.
- W2012503494 hasOpenAccess W2012503494 @default.
- W2012503494 hasPrimaryLocation W20125034941 @default.
- W2012503494 hasRelatedWork W1969108390 @default.
- W2012503494 hasRelatedWork W2059850670 @default.
- W2012503494 hasRelatedWork W2116433048 @default.
- W2012503494 hasRelatedWork W2267777515 @default.
- W2012503494 hasRelatedWork W2372649272 @default.
- W2012503494 hasRelatedWork W2382463420 @default.
- W2012503494 hasRelatedWork W2405140048 @default.