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- W2012504841 abstract "We thank Dr Tejpal Gupta for his interest in the consensus recommendations. Regarding the 4-week period of no change in anti-neoplastic therapy and bisphosphonate: in order to assess response to a specific intervention, an appropriate period is required for making that assessment. We appreciate Dr Gupta's concern and in fact, this dilemma was debated among some of us involved in this consensus. The Consensus Working Party considers a 4-week period as a reasonable compromise in allowing assessment of the treatment intervention alone, recognizing that (a) some patients respond sooner, and some respond later than 4 weeks after radiation; and (b) patients cannot postpone other systemic interventions indefinitely. As the title of our paper implies, the final agreement derived from the consensus. There should be no intended change in systemic chemo- or hormonal therapy or bisphophonates for 4 weeks before and after the delivery of radiotherapy. If disease or pain progresses necessitating such a change during this period, these patients will be analyzed under the category of pain progression by intention-to-treat principle." @default.
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- W2012504841 date "2003-05-01" @default.
- W2012504841 modified "2023-10-16" @default.
- W2012504841 title "REPLY TO LETTER TO THE EDITOR, REGARDING OUR PAPER “INTERNATIONAL CONSENSUS ON PALLIATIVE RADIOTHERAPY ENDPOINTS FOR FUTURE CLINICAL TRIALS IN BONE METASTASES”" @default.
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