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- W2012506172 abstract "Background and Methods The purpose of this annual article is to highlight and briefly review new and significant information on agents that may be teratogenic in pregnant women. Various sources of on-line and printed information are given. Results The following topics have been discussed: 1) lithium medication: decreased estimate of risk; 2) cigarette smoking and genotype as contributors to oral-facial clefts and clubfoot; 3) trimethoprim; 4) methimazole syndrome?; 5) glucocorticoids and oral-facial clefts; 6) binge drinking; 7) fetal valproate syndrome; and 8) carbamazepine. Conclusions We have highlighted several maternal exposures during pregnancy that are associated with small but increased rates of birth defects, generally only a few cases per 1,000 infants. These exposures include cigarette smoking, and treatment with lithium, trimethoprim, methimazole, or corticosteroids. This weak teratogenic effect was usually identified by the linkage of an uncommon treatment with an unusual birth defect outcome. The use of modern epidemiologic techniques, especially prospective multicenter studies that provide increased numbers, has helped to strengthen the evidence for these associations. We discuss how teratogenic risks that are small in comparison to the background risk can be presented to at-risk women and their doctors. We have briefly listed some elements that might be used in prioritizing further studies of suspected teratogenic exposures. Various existing methods for expressing the strength of evidence for human teratogenicity are also given. Teratology 65:153–161, 2002. © 2002 Wiley-Liss, Inc." @default.
- W2012506172 created "2016-06-24" @default.
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- W2012506172 date "2002-03-12" @default.
- W2012506172 modified "2023-10-17" @default.
- W2012506172 title "Update on new developments in the study of human teratogens" @default.
- W2012506172 cites W125743501 @default.
- W2012506172 cites W1925224829 @default.
- W2012506172 cites W1963768404 @default.
- W2012506172 cites W1970202482 @default.
- W2012506172 cites W1970647064 @default.
- W2012506172 cites W1972616909 @default.
- W2012506172 cites W1974475255 @default.
- W2012506172 cites W1974786333 @default.
- W2012506172 cites W1979432994 @default.
- W2012506172 cites W1986298824 @default.
- W2012506172 cites W1992786167 @default.
- W2012506172 cites W1994872919 @default.
- W2012506172 cites W1999055847 @default.
- W2012506172 cites W2015235882 @default.
- W2012506172 cites W2022794082 @default.
- W2012506172 cites W2024493563 @default.
- W2012506172 cites W2030009242 @default.
- W2012506172 cites W2033750580 @default.
- W2012506172 cites W2035285899 @default.
- W2012506172 cites W2036259752 @default.
- W2012506172 cites W2037342900 @default.
- W2012506172 cites W2037741429 @default.
- W2012506172 cites W2039280134 @default.
- W2012506172 cites W2041134324 @default.
- W2012506172 cites W2042565968 @default.
- W2012506172 cites W2042715664 @default.
- W2012506172 cites W2045306023 @default.
- W2012506172 cites W2047241525 @default.
- W2012506172 cites W2048046716 @default.
- W2012506172 cites W2051047506 @default.
- W2012506172 cites W2052712925 @default.
- W2012506172 cites W2054422213 @default.
- W2012506172 cites W2057801246 @default.
- W2012506172 cites W2066391974 @default.
- W2012506172 cites W2069279852 @default.
- W2012506172 cites W2072070188 @default.
- W2012506172 cites W2073255901 @default.
- W2012506172 cites W2076079082 @default.
- W2012506172 cites W2077289141 @default.
- W2012506172 cites W2079119641 @default.
- W2012506172 cites W2082984319 @default.
- W2012506172 cites W2084879395 @default.
- W2012506172 cites W2088226568 @default.
- W2012506172 cites W2090763178 @default.
- W2012506172 cites W2091856481 @default.
- W2012506172 cites W2091908600 @default.
- W2012506172 cites W2093084078 @default.
- W2012506172 cites W2099302241 @default.
- W2012506172 cites W2103849147 @default.
- W2012506172 cites W2104260218 @default.
- W2012506172 cites W2110510882 @default.
- W2012506172 cites W2124914558 @default.
- W2012506172 cites W2126218665 @default.
- W2012506172 cites W2133358938 @default.
- W2012506172 cites W2142987588 @default.
- W2012506172 cites W2143268844 @default.
- W2012506172 cites W2146007145 @default.
- W2012506172 cites W2147848178 @default.
- W2012506172 cites W2159568537 @default.
- W2012506172 cites W2161076504 @default.
- W2012506172 cites W2162933447 @default.
- W2012506172 cites W2164174681 @default.
- W2012506172 cites W2168922114 @default.
- W2012506172 cites W2185253654 @default.
- W2012506172 cites W2315775430 @default.
- W2012506172 cites W2325560622 @default.
- W2012506172 cites W2325954328 @default.
- W2012506172 cites W2346153620 @default.
- W2012506172 cites W2426176320 @default.
- W2012506172 cites W2914200902 @default.
- W2012506172 cites W4230246096 @default.
- W2012506172 cites W4233128187 @default.
- W2012506172 cites W4234883984 @default.
- W2012506172 cites W4236028761 @default.
- W2012506172 cites W4236235450 @default.
- W2012506172 cites W4241656044 @default.
- W2012506172 cites W4243550072 @default.
- W2012506172 cites W4244214422 @default.
- W2012506172 cites W4244234317 @default.
- W2012506172 cites W4300127172 @default.
- W2012506172 cites W4319590510 @default.
- W2012506172 cites W4361867701 @default.
- W2012506172 cites W4375926802 @default.
- W2012506172 cites W4383067671 @default.
- W2012506172 doi "https://doi.org/10.1002/tera.10032" @default.
- W2012506172 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11948561" @default.