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- W2012506661 abstract "Objective: To evaluate the effect of exenatide on clinical parameters in obese patients with type 2 diabetes mellitus whose hyperglycemia is not adequately controlled despite treatment with oral hypoglycemic agents and insulin.Methods: In this retrospective analysis, clinical progress of 52 obese patients with type 2 diabetes treated with exenatide, 5 mcg twice daily, in an outpatient setting was reviewed. Treatment initiation was between September and December 2005. Mean follow-up period was 26 weeks. Thirty-eight patients took exenatide regularly (Group A); 14 patients discontinued exenatide because of insurance, personal, or economic reasons (Group B). Measurements at baseline and at follow-up included body weight; blood pressure; and levels of hemoglobin A1c (HbA1c), high-sensitivity C-reactive protein (CRP), and plasma lipids. Insulin dosage requirements were assessed.Results: Mean body weight (± standard error of the mean) decreased by 6.46 ± 0.8 kg (P<.001) in Group A and increased by 2.4 ± 0.6 kg ..." @default.
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- W2012506661 date "2007-01-01" @default.
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- W2012506661 title "Exenatide Therapy in Obese Patients With Type 2 Diabetes Mellitus Treated with Insulin" @default.
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- W2012506661 doi "https://doi.org/10.4158/ep.13.5.444" @default.
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