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- W2012511976 abstract "1 A series of experiments were conducted to investigate the effects of dietary retinol status on chickens ingesting aflatoxin B 1 . The effects of dietary supplementation with biotin and α-tocopherol were also examined. 2. Aflatoxin B 1 levels greater than I mg/kg diet had a detrimental effect on ‘liveability’, body-weight gain, food intake and food conversion efficiency. When fed for more than 2 weeks aflatoxin increased relative liver weight and liver lipid concentration. These effects were less pronounced with avitaminotic A chickens. 3. A synergistic effect on hydropericardium development was observed between aflatoxin B, and retinol. This effect was not observed when the dietary level of α-tocopherol was increased tenfold. 4. The specific activities of certain hepatic lipogenic and amino acid-metabolizing enzymes were influenced by aflatoxin ingestion. A reduction in lipogenic enzyme activity was observed before a reduction in the activities of amino acid-metabolizing enzymes. 5. Liver fatty acid composition was significantly influenced by aflatoxin B 1 . The extent of these changes was reduced by the inclusion of additional dietary biotin." @default.
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- W2012511976 date "1979-05-01" @default.
- W2012511976 modified "2023-09-26" @default.
- W2012511976 title "The influence of vitamin A status on the response of chickens to aflatoxin B1and changes in liver lipid metabolism associated with aflatoxicosis" @default.
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- W2012511976 doi "https://doi.org/10.1079/bjn19790068" @default.
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