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- W2012538568 abstract "Retinoic acid (RA) stimulated the production of erythropoietin (Epo) in a human hepatoma cell line, HepG2 cells. The stimulation was due to the accumulation of Epo mRNA. The Epo production in HepG2 cells was also dependent on O 2 tension for cell culture but the enhancement of Epo production by RA was independent of O 2 tension, indicating that RA exerts its effect through a pathway different from O 2 . Oral administration of RA to the vitamin A‐depleted rats elevated the concentration of Epo in serum. These results suggest that RA up‐regulates EPO production in vivo as well as in vitro." @default.
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- W2012538568 date "1994-08-01" @default.
- W2012538568 modified "2023-10-12" @default.
- W2012538568 title "Retinoic acid up‐regulates erythropoietin production in hepatoma cells and in vitamin A‐depleted rats" @default.
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- W2012538568 doi "https://doi.org/10.1016/0014-5793(94)00673-3" @default.
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