FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012544518> ?p ?o ?g. }

• W2012544518 abstract "Abstract Dicyclohexylcarbodiimide (DCCD), a potent inhibitor of the F0F1-type H+-translocating ATPase, was employed to determine the possible involvement of such an ATPase in urinary acidification. Two methods were used in this approach: (1) the reaction of [14C]DCCD with tissues involved in urinary acidification and (2) the inhibition of ATPase activity by DCCD. Membrane components from epithelial cells of toad and turtle urinary bladder and brush borders of rabbit kidney were reacted with [14C]DCCD and analyzed by polyacrylamide gel electrophoresis both before and after extraction with organic solvents. Although a DCCD-binding component was extracted from toad and turtle bladder membranes by chloroform/methanol (2:1, v v ), the binding was not saturable. Analysis of this DCCD-binding component by thin-layer chromatography indicated that there was no ninhydrin reactivity associated with the [14C]DCCD binding. Moreover, all attempts to precipitate a DCCD-binding protein were unsuccessful. This and other evidence suggested that the observed DCCD binding was to phospholipid. In the second type of experiments, the ATPase activity present in brush borders from rabbit kidney was partially inhibited by DCCD, but at a concentration that is over two orders of magnitude greater than that required for typical DCCD-sensitive ATPase. We conclude from our failure to find positive evidence of a DCCD-reactive protein and from the relative insensitivity of the ATPase to DCCD that either urinary acidification is not accomplished by a typical F0F1-type translocating ATPase, or the F0 has been modified so that the sensitivity to DCCD has been altered or lost." @default.
• W2012544518 created "2016-06-24" @default.
• W2012544518 creator A5030221631 @default.
• W2012544518 creator A5066577721 @default.
• W2012544518 date "1982-05-01" @default.
• W2012544518 modified "2023-09-27" @default.
• W2012544518 title "Proton-transporting urinary epithelia. Reactivity with N,N′-dicyclohexylcarbodiimide" @default.
• W2012544518 cites W1479788934 @default.
• W2012544518 cites W1484115451 @default.
• W2012544518 cites W1488730449 @default.
• W2012544518 cites W1491387027 @default.
• W2012544518 cites W1508115748 @default.
• W2012544518 cites W1556910033 @default.
• W2012544518 cites W1563180393 @default.
• W2012544518 cites W1582740601 @default.
• W2012544518 cites W1593271255 @default.
• W2012544518 cites W1595204022 @default.
• W2012544518 cites W1602271438 @default.
• W2012544518 cites W1731782390 @default.
• W2012544518 cites W1775749144 @default.
• W2012544518 cites W1973277558 @default.
• W2012544518 cites W1973640226 @default.
• W2012544518 cites W1976163575 @default.
• W2012544518 cites W1977340994 @default.
• W2012544518 cites W1982743844 @default.
• W2012544518 cites W1985342306 @default.
• W2012544518 cites W1987443198 @default.
• W2012544518 cites W1988520285 @default.
• W2012544518 cites W1998222137 @default.
• W2012544518 cites W2002806366 @default.
• W2012544518 cites W2020644765 @default.
• W2012544518 cites W2022246809 @default.
• W2012544518 cites W2034882625 @default.
• W2012544518 cites W2037099660 @default.
• W2012544518 cites W2040694105 @default.
• W2012544518 cites W2044242683 @default.
• W2012544518 cites W2062577754 @default.
• W2012544518 cites W2080240343 @default.
• W2012544518 cites W2083398148 @default.
• W2012544518 cites W2087791794 @default.
• W2012544518 cites W2087937052 @default.
• W2012544518 cites W2088966535 @default.
• W2012544518 cites W2089370166 @default.
• W2012544518 cites W2104055613 @default.
• W2012544518 cites W2120710805 @default.
• W2012544518 cites W2134413315 @default.
• W2012544518 cites W2201080739 @default.
• W2012544518 cites W2397011126 @default.
• W2012544518 cites W2413426507 @default.
• W2012544518 cites W2463014555 @default.
• W2012544518 cites W4244034700 @default.
• W2012544518 doi "https://doi.org/10.1016/0005-2728(82)90006-8" @default.
• W2012544518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6212080" @default.
• W2012544518 hasPublicationYear "1982" @default.
• W2012544518 type Work @default.
• W2012544518 sameAs 2012544518 @default.
• W2012544518 citedByCount "3" @default.
• W2012544518 crossrefType "journal-article" @default.
• W2012544518 hasAuthorship W2012544518A5030221631 @default.
• W2012544518 hasAuthorship W2012544518A5066577721 @default.
• W2012544518 hasConcept C142724271 @default.
• W2012544518 hasConcept C149997192 @default.
• W2012544518 hasConcept C181199279 @default.
• W2012544518 hasConcept C185592680 @default.
• W2012544518 hasConcept C18903297 @default.
• W2012544518 hasConcept C204787440 @default.
• W2012544518 hasConcept C23265538 @default.
• W2012544518 hasConcept C2776910235 @default.
• W2012544518 hasConcept C2778166480 @default.
• W2012544518 hasConcept C43617362 @default.
• W2012544518 hasConcept C55493867 @default.
• W2012544518 hasConcept C71924100 @default.
• W2012544518 hasConcept C86803240 @default.
• W2012544518 hasConceptScore W2012544518C142724271 @default.
• W2012544518 hasConceptScore W2012544518C149997192 @default.
• W2012544518 hasConceptScore W2012544518C181199279 @default.
• W2012544518 hasConceptScore W2012544518C185592680 @default.
• W2012544518 hasConceptScore W2012544518C18903297 @default.
• W2012544518 hasConceptScore W2012544518C204787440 @default.
• W2012544518 hasConceptScore W2012544518C23265538 @default.
• W2012544518 hasConceptScore W2012544518C2776910235 @default.
• W2012544518 hasConceptScore W2012544518C2778166480 @default.
• W2012544518 hasConceptScore W2012544518C43617362 @default.
• W2012544518 hasConceptScore W2012544518C55493867 @default.
• W2012544518 hasConceptScore W2012544518C71924100 @default.
• W2012544518 hasConceptScore W2012544518C86803240 @default.
• W2012544518 hasLocation W20125445181 @default.
• W2012544518 hasLocation W20125445182 @default.
• W2012544518 hasOpenAccess W2012544518 @default.
• W2012544518 hasPrimaryLocation W20125445181 @default.
• W2012544518 hasRelatedWork W1982557437 @default.
• W2012544518 hasRelatedWork W2059044160 @default.
• W2012544518 hasRelatedWork W2343304726 @default.
• W2012544518 hasRelatedWork W2397218192 @default.
• W2012544518 hasRelatedWork W2949409014 @default.
• W2012544518 hasRelatedWork W2950003723 @default.
• W2012544518 hasRelatedWork W2950863597 @default.
• W2012544518 hasRelatedWork W3008718849 @default.
• W2012544518 hasRelatedWork W3136937210 @default.
• W2012544518 hasRelatedWork W4244767111 @default.

• next