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• W2012562786 startingPage "23" @default.
• W2012562786 abstract "Utilization of biodegradable polymeric materials as delivery agents in dermatology Fiorenza Rancan, Ulrike Blume-Peytavi, Annika VogtClinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité – Universitätsmedizin Berlin, GermanyAbstract: Biodegradable polymeric materials are ideal carrier systems for biomedical applications. Features like controlled and sustained delivery, improved drug pharmacokinetics, reduced side effects and safe degradation make the use of these materials very attractive in a lot of medical fields, with dermatology included. A number of studies have shown that particle-based formulations can improve the skin penetration of topically applied drugs. However, for a successful translation of these promising results into a clinical application, a more rational approach is needed to take into account the different properties of diseased skin and the fate of these polymeric materials after topical application. In fact, each pathological skin condition poses different challenges and the way diseased skin interacts with polymeric carriers might be markedly different to that of healthy skin. In most inflammatory skin conditions, the skin&#39;s barrier is impaired and the local immune system is activated. A better understanding of such mechanisms has the potential to improve the efficacy of carrier-based dermatotherapy. Such knowledge would allow the informed choice of the type of polymeric carrier depending on the skin condition to be treated, the type of drug to be loaded, and the desired release kinetics. Furthermore, a better control of polymer degradation and release properties in accordance with the skin environment would improve the safety and the selectivity of drug release. This review aims at summarizing the current knowledge on how polymeric delivery systems interact with healthy and diseased skin, giving an overview of the challenges that different pathological skin conditions pose to the development of safer and more specific dermatotherapies.Keywords: nanocarriers, nanoparticles, biodegradable polymers, skin penetration, hair follicles" @default.
• W2012562786 created "2016-06-24" @default.
• W2012562786 creator A5015290431 @default.
• W2012562786 creator A5037986822 @default.
• W2012562786 creator A5089674181 @default.
• W2012562786 date "2014-01-01" @default.
• W2012562786 modified "2023-10-02" @default.
• W2012562786 title "Utilization of biodegradable polymeric materials as delivery agents in dermatology" @default.
• W2012562786 cites W1273743834 @default.
• W2012562786 cites W1505403039 @default.
• W2012562786 cites W1524212713 @default.
• W2012562786 cites W1589480349 @default.
• W2012562786 cites W1595426294 @default.
• W2012562786 cites W1604173330 @default.
• W2012562786 cites W17288121 @default.
• W2012562786 cites W1729031502 @default.
• W2012562786 cites W1965042724 @default.
• W2012562786 cites W1966239530 @default.
• W2012562786 cites W1968548096 @default.
• W2012562786 cites W1968865208 @default.
• W2012562786 cites W1969551291 @default.
• W2012562786 cites W1970130895 @default.
• W2012562786 cites W1970883344 @default.
• W2012562786 cites W1971873338 @default.
• W2012562786 cites W1973265843 @default.
• W2012562786 cites W1976677427 @default.
• W2012562786 cites W1978537309 @default.
• W2012562786 cites W1981760171 @default.
• W2012562786 cites W1982749658 @default.
• W2012562786 cites W1984013252 @default.
• W2012562786 cites W1984121549 @default.
• W2012562786 cites W1988851509 @default.
• W2012562786 cites W1989038320 @default.
• W2012562786 cites W1997877282 @default.
• W2012562786 cites W1997978522 @default.
• W2012562786 cites W1999313103 @default.
• W2012562786 cites W2004755607 @default.
• W2012562786 cites W2006408941 @default.
• W2012562786 cites W2007350878 @default.
• W2012562786 cites W2007656823 @default.
• W2012562786 cites W2012056239 @default.
• W2012562786 cites W2013482629 @default.
• W2012562786 cites W2016711291 @default.
• W2012562786 cites W2017364759 @default.
• W2012562786 cites W2019612609 @default.
• W2012562786 cites W2022244556 @default.
• W2012562786 cites W2023283179 @default.
• W2012562786 cites W2030652623 @default.
• W2012562786 cites W2032679003 @default.
• W2012562786 cites W2039290751 @default.
• W2012562786 cites W2040960783 @default.
• W2012562786 cites W2041000069 @default.
• W2012562786 cites W2041122272 @default.
• W2012562786 cites W2043941772 @default.
• W2012562786 cites W2044185990 @default.
• W2012562786 cites W2045525047 @default.
• W2012562786 cites W2045698271 @default.
• W2012562786 cites W2047609968 @default.
• W2012562786 cites W2047886285 @default.
• W2012562786 cites W2049269927 @default.
• W2012562786 cites W2049942080 @default.
• W2012562786 cites W2050559479 @default.
• W2012562786 cites W2051996335 @default.
• W2012562786 cites W2054083814 @default.
• W2012562786 cites W2055574464 @default.
• W2012562786 cites W2055704035 @default.
• W2012562786 cites W2056407250 @default.
• W2012562786 cites W2057437898 @default.
• W2012562786 cites W2058500357 @default.
• W2012562786 cites W2060879575 @default.
• W2012562786 cites W2061016693 @default.
• W2012562786 cites W2062330454 @default.
• W2012562786 cites W2064999317 @default.
• W2012562786 cites W2065025122 @default.
• W2012562786 cites W2065162705 @default.
• W2012562786 cites W2066061512 @default.
• W2012562786 cites W2067393327 @default.
• W2012562786 cites W2068517215 @default.
• W2012562786 cites W2070174418 @default.
• W2012562786 cites W2074167190 @default.
• W2012562786 cites W2079965037 @default.
• W2012562786 cites W2080102851 @default.
• W2012562786 cites W2081164178 @default.
• W2012562786 cites W2082724339 @default.
• W2012562786 cites W2084879398 @default.
• W2012562786 cites W2085465573 @default.
• W2012562786 cites W2087731154 @default.
• W2012562786 cites W2089773350 @default.
• W2012562786 cites W2096054643 @default.
• W2012562786 cites W2096195586 @default.
• W2012562786 cites W2098296223 @default.
• W2012562786 cites W2100287780 @default.
• W2012562786 cites W2102051171 @default.
• W2012562786 cites W2102449174 @default.
• W2012562786 cites W2107283881 @default.
• W2012562786 cites W2109830142 @default.
• W2012562786 cites W2112569571 @default.
• W2012562786 cites W2115741721 @default.

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