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• W2012563419 abstract "Although conventional immunosuppressive agents such as calcineurin inhibitors, have substantially reduced the risk of acute rejection, they have had less impact on the long-term survival. This is likely to be related to the adverse effects of such agents in terms of impaired renal function, hypertension, and dyslipidemia. These pitfalls of the currently available agents stimulated the research for biologic agents. Several biologic agents are now in development and hold promise for improved long-term outcomes in renal transplant recipients, particularly in those who receive sub-optimal organs. This article gives an overview of these new biological agents with particular emphasis on belatacept and their possible impact on short- and long-term outcomes, notably on marginal organs." @default.
• W2012563419 created "2016-06-24" @default.
• W2012563419 creator A5028813168 @default.
• W2012563419 creator A5074560478 @default.
• W2012563419 date "2012-12-02" @default.
• W2012563419 modified "2023-10-18" @default.
• W2012563419 title "The role of belataceptin transplantation: results and implications of clinical trials in the context of other new biological immunosuppressant agents" @default.
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• W2012563419 doi "https://doi.org/10.1111/ctr.12044" @default.
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• W2012563419 hasPublicationYear "2012" @default.
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