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- W2012591522 endingPage "146" @default.
- W2012591522 startingPage "139" @default.
- W2012591522 abstract "Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by hemolytic anemia caused by fragmentation of erythrocytes and thrombocytopenia due to increased platelet aggregation and thrombus formation, eventually leading to disturbed microcirculation with reduced organ perfusion. Although several disease states may manifest as TMA, the two most relevant conditions associated with TMA are thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), characterized by prominent brain or renal lesions, respectively. However, occasionally the clinical distinction between these two conditions can be difficult. In this review, we focus on the epidemiologic and diagnostic criteria as well as on the most recent insights into the pathophysiology and treatment of these two conditions." @default.
- W2012591522 created "2016-06-24" @default.
- W2012591522 creator A5030222224 @default.
- W2012591522 date "2006-06-01" @default.
- W2012591522 modified "2023-10-16" @default.
- W2012591522 title "Thrombotic microangiopathies: An update" @default.
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