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- W2012594969 abstract "A novel mutation of the p53 gene has been found in a rat hepatoma cell line, FAA-HTC1.This cell line carried two kinds of abnormal p53 transcripts; one lacked the exon 8 sequence, and the other had a single base substitution G to T which resulted in a new stop codon in exon 8. In the genomic DNA, this base substitution in exon 8 was present, indicating that both transcripts were transcribed from the mutated gene. No mutation was detected in its two flanking introns. In this cell line, the exon-deleted transcript seems to be generated by exon skipping due to an unknownmechanismother than splice site mutations." @default.
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- W2012594969 date "1992-01-01" @default.
- W2012594969 modified "2023-10-02" @default.
- W2012594969 title "Alternatively-Spliced p53 mRNA in the FAA-HTC1 Rat Hepatoma Cell Line without the Splice Site Mutations." @default.
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- W2012594969 doi "https://doi.org/10.1247/csf.17.427" @default.
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