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- W2012596312 abstract "Administration of dibutyryl-3′,5′-cyclic AMP to rats caused marked, but temporary, decrease of liver glutathione. This decrease appeared to be catalyzed by γ-glutamyltransferase, because it occured concomitantly with induction of the enzyme and increase of cysteine in the liver. The biological half-life of hepatic γ-glutamyltransferase was estimated to be about 3 hours. It is proposed that the physiological levels of glutathione and γ-glutamyltransferase in the liver are controlled by 3′,5′-cyclic AMP, and that liver glutathione may serve as a reservoir of cysteine, which can be mobilized by the transferase." @default.
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- W2012596312 date "1976-02-01" @default.
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- W2012596312 title "Decrease of glutathione and induction of γ-glutamyltransferase by dibutyryl-3′,5′-cyclic AMP in rat liver" @default.
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- W2012596312 doi "https://doi.org/10.1016/0006-291x(76)90335-1" @default.
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