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- W2012605415 abstract "Intracranial drug self-administration (ICSA) offers a relatively new approach for investigating the neurobiological mechanisms involved in brain reinforcement processes. Discrete brain regions responsible for the initiation of neuronal activity associated with the response-contingent delivery of a drug reinforcer can be identified using these procedures since the drug is infused directly into a specific brain locus. In the last decade, several papers have appeared in the literature reporting the self-administration of various substances into a number of brain regions. However, different laboratories often employ diverse methodological procedures to demonstrate ICSA, and this can lead to erroneous conclusions when comparing data from different investigations. This review presents a critical evaluation of the current status of research in this area and suggests behavioral as well as methodological guidelines for future investigations to follow." @default.
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- W2012605415 date "1987-09-01" @default.
- W2012605415 modified "2023-09-23" @default.
- W2012605415 title "Intracranial self-administration methodologies" @default.
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- W2012605415 doi "https://doi.org/10.1016/s0149-7634(87)80017-9" @default.
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