FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012606730> ?p ?o ?g. }

• W2012606730 endingPage "267" @default.
• W2012606730 startingPage "261" @default.
• W2012606730 abstract "To assess the effect of transdermal vs. oral administration of E2 on plasma homocysteine levels and to evaluate the impact of adding a progestogen to these regimens.Prospective, double-blind, double-dummy, placebo-controlled study.Outpatient clinics in two university hospitals and two teaching hospitals in The Netherlands.One hundred fifty-two healthy hysterectomized postmenopausal women.Thirteen 28-day treatment cycles with placebo (n = 49); transdermal 17beta-E2, 50 microg (n = 33), oral E2, 1 mg (n = 37), or oral E2, 1 mg, plus gestodene, 25 microg (n = 33), followed by four cycles of placebo in each group.Fasting plasma total homocysteine concentrations at baseline and cycle 4, 13, and 17.Mean (+/-SD) homocysteine concentrations in the oral E2 group decreased from baseline to cycle 4 (9.0 +/- 2.5 micromol/L vs. 8.2 +/- 2.0 micromol/L; mean change, -7.6%). Homocystine values in the oral E2 plus gestodene group did not change substantially from baseline to cycle 4 (8.9 +/- 1.6 micromol/L vs. 8.6 +/- 2.0 micromol/L; mean change, -4.4%). No significant changes were observed in the transdermal E2 group. After four washout cycles, the homocysteine concentration had returned to baseline values in all groups.Oral E2 therapy reduced the homocysteine concentration more than did therapy with transdermal E2 or oral E2 plus gestodene. This finding may indicate a role of liver metabolism and suggests that gestodene has a negative effect on these changes." @default.
• W2012606730 created "2016-06-24" @default.
• W2012606730 creator A5016620300 @default.
• W2012606730 creator A5022234156 @default.
• W2012606730 creator A5025928187 @default.
• W2012606730 creator A5027467733 @default.
• W2012606730 creator A5034626585 @default.
• W2012606730 creator A5045835727 @default.
• W2012606730 creator A5051560890 @default.
• W2012606730 creator A5073286371 @default.
• W2012606730 date "2003-02-01" @default.
• W2012606730 modified "2023-09-27" @default.
• W2012606730 title "A randomized placebo-controlled study of the effect of transdermal vs. oral estradiol with or without gestodene on homocysteine levels" @default.
• W2012606730 cites W1582396128 @default.
• W2012606730 cites W1971189149 @default.
• W2012606730 cites W1975357252 @default.
• W2012606730 cites W2005375443 @default.
• W2012606730 cites W2012974823 @default.
• W2012606730 cites W2026865152 @default.
• W2012606730 cites W2031469248 @default.
• W2012606730 cites W2047298742 @default.
• W2012606730 cites W2070927434 @default.
• W2012606730 cites W2076460856 @default.
• W2012606730 cites W2087097104 @default.
• W2012606730 cites W2090379661 @default.
• W2012606730 cites W2090737929 @default.
• W2012606730 cites W2099711578 @default.
• W2012606730 cites W2108484297 @default.
• W2012606730 cites W2124277715 @default.
• W2012606730 cites W2128191051 @default.
• W2012606730 cites W2143004063 @default.
• W2012606730 cites W2153848274 @default.
• W2012606730 cites W2164208824 @default.
• W2012606730 cites W2239542423 @default.
• W2012606730 cites W2320812405 @default.
• W2012606730 cites W2333702587 @default.
• W2012606730 cites W4239075380 @default.
• W2012606730 doi "https://doi.org/10.1016/s0015-0282(02)04661-7" @default.
• W2012606730 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12568832" @default.
• W2012606730 hasPublicationYear "2003" @default.
• W2012606730 type Work @default.
• W2012606730 sameAs 2012606730 @default.
• W2012606730 citedByCount "30" @default.
• W2012606730 crossrefType "journal-article" @default.
• W2012606730 hasAuthorship W2012606730A5016620300 @default.
• W2012606730 hasAuthorship W2012606730A5022234156 @default.
• W2012606730 hasAuthorship W2012606730A5025928187 @default.
• W2012606730 hasAuthorship W2012606730A5027467733 @default.
• W2012606730 hasAuthorship W2012606730A5034626585 @default.
• W2012606730 hasAuthorship W2012606730A5045835727 @default.
• W2012606730 hasAuthorship W2012606730A5051560890 @default.
• W2012606730 hasAuthorship W2012606730A5073286371 @default.
• W2012606730 hasBestOaLocation W20126067301 @default.
• W2012606730 hasConcept C126322002 @default.
• W2012606730 hasConcept C134018914 @default.
• W2012606730 hasConcept C142724271 @default.
• W2012606730 hasConcept C204787440 @default.
• W2012606730 hasConcept C205679159 @default.
• W2012606730 hasConcept C27081682 @default.
• W2012606730 hasConcept C2777056448 @default.
• W2012606730 hasConcept C2777090595 @default.
• W2012606730 hasConcept C2777164284 @default.
• W2012606730 hasConcept C2778239997 @default.
• W2012606730 hasConcept C2779076696 @default.
• W2012606730 hasConcept C2780572241 @default.
• W2012606730 hasConcept C2908647359 @default.
• W2012606730 hasConcept C2986817661 @default.
• W2012606730 hasConcept C71924100 @default.
• W2012606730 hasConcept C98274493 @default.
• W2012606730 hasConcept C99454951 @default.
• W2012606730 hasConceptScore W2012606730C126322002 @default.
• W2012606730 hasConceptScore W2012606730C134018914 @default.
• W2012606730 hasConceptScore W2012606730C142724271 @default.
• W2012606730 hasConceptScore W2012606730C204787440 @default.
• W2012606730 hasConceptScore W2012606730C205679159 @default.
• W2012606730 hasConceptScore W2012606730C27081682 @default.
• W2012606730 hasConceptScore W2012606730C2777056448 @default.
• W2012606730 hasConceptScore W2012606730C2777090595 @default.
• W2012606730 hasConceptScore W2012606730C2777164284 @default.
• W2012606730 hasConceptScore W2012606730C2778239997 @default.
• W2012606730 hasConceptScore W2012606730C2779076696 @default.
• W2012606730 hasConceptScore W2012606730C2780572241 @default.
• W2012606730 hasConceptScore W2012606730C2908647359 @default.
• W2012606730 hasConceptScore W2012606730C2986817661 @default.
• W2012606730 hasConceptScore W2012606730C71924100 @default.
• W2012606730 hasConceptScore W2012606730C98274493 @default.
• W2012606730 hasConceptScore W2012606730C99454951 @default.
• W2012606730 hasIssue "2" @default.
• W2012606730 hasLocation W20126067301 @default.
• W2012606730 hasLocation W20126067302 @default.
• W2012606730 hasOpenAccess W2012606730 @default.
• W2012606730 hasPrimaryLocation W20126067301 @default.
• W2012606730 hasRelatedWork W1963710704 @default.
• W2012606730 hasRelatedWork W1995050400 @default.
• W2012606730 hasRelatedWork W1995647897 @default.
• W2012606730 hasRelatedWork W2013481652 @default.
• W2012606730 hasRelatedWork W2027180407 @default.
• W2012606730 hasRelatedWork W2101821182 @default.

• next