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• W2012624239 abstract "Abstract: Objective: Heart transplantation improves the survival rate and quality of life in patients with severe symptoms of congestive heart failure and an ejection fraction of 20% or less. Despite marked symptomatic and clinical improvement in those who undergo heart transplantation, exercise capacity often remains reduced, and the factors limiting exercise performance during the post-transplantation period remain unclear. This study was performed to investigate the factors affecting exercise capacity in heart transplantation recipients. Patients and methods: Fourteen patients with cardiomyopathy were enrolled in this study. We measured peak exercise oxygen uptake (peak VO2) in seven patients (age range: 42 ± 14 yr) 10–28 months after transplantation, in seven patients (age range: 33 ± 18 yr) with dilated cardiomyopathy before heart transplantation, and in 14 healthy control subjects (age range: 44 ± 12 yr). The left ventricular ejection fraction, Beck Depression Inventory score, Medical Outcome Health Survey Short Form-36 Questionnaire (SF-36) results, and immunosuppressive therapy administered were recorded in all patient groups. Results: All patients in the post-transplantation group terminated exercise testing before the anaerobic threshold because of general fatigue. All heart transplantation recipients exhibited a left ventricular ejection fraction within the normal range (mean ± SD = 57% ± 2%). The peak VO2 mean values were significantly different among the three groups (p = 0.001). There were statistically significant correlations between the peak VO2 values and the Beck Depression Inventory scores (r = −0.637, p = 0.01), between the peak VO2 values and bodily pain (r = 0.717, p = 0.006), between the peak VO2 values and general health perceptions (r = 0.706, p = 0.007), and between peak VO2 values and postoperative duration (r = 0.843, p = 0.03) in all patient groups. Conclusion: In the long-term treatment of heart transplant recipients, exercise training should be considered an important therapeutic tool that enables patients to achieve a good quality of life." @default.
• W2012624239 created "2016-06-24" @default.
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• W2012624239 date "2007-05-01" @default.
• W2012624239 modified "2023-10-15" @default.
• W2012624239 title "Assessing exercise performance after heart transplantation" @default.
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• W2012624239 doi "https://doi.org/10.1111/j.1399-0012.2007.00658.x" @default.
• W2012624239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17488391" @default.
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