Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012634577> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2012634577 endingPage "480" @default.
- W2012634577 startingPage "473" @default.
- W2012634577 abstract "In this paper, we reviewed our recent works on a possible link between molecular evolution and tissue evolution. The evolutionary rates of genes that are expressed tissue specifically were shown to differ widely to one another, depending on tissues: Brain specific genes evolve with significantly slower rate than immune specific genes. The tissue dependence of molecular evolutionary rate strongly suggests the presence of functional constraints against molecular changes from tissue level. A molecular phylogenetic analysis of tissue specific isoforms that are identical to one another in function, but differ only in tissue distribution revealed frequent gene duplications and rapid accumulations of amino acid substitutions during the early evolution of chordates, where rapid evolution at the tissue or organ levels is thought to have occurred. On the basis of functional constraints, a possible explanation for the correlation between evolution at the two levels was presented." @default.
- W2012634577 created "2016-06-24" @default.
- W2012634577 creator A5014604969 @default.
- W2012634577 creator A5026687937 @default.
- W2012634577 creator A5039946998 @default.
- W2012634577 creator A5061633444 @default.
- W2012634577 date "1994-01-01" @default.
- W2012634577 modified "2023-09-26" @default.
- W2012634577 title "A possible link between molecular evolution and tissue evolution demonstrated by tissue specific genes." @default.
- W2012634577 cites W1993054962 @default.
- W2012634577 cites W1993351732 @default.
- W2012634577 cites W1997675834 @default.
- W2012634577 cites W2008265915 @default.
- W2012634577 cites W2009851083 @default.
- W2012634577 cites W2032051413 @default.
- W2012634577 cites W2052923559 @default.
- W2012634577 cites W2058212562 @default.
- W2012634577 cites W3012079654 @default.
- W2012634577 doi "https://doi.org/10.1266/jjg.69.473" @default.
- W2012634577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7999368" @default.
- W2012634577 hasPublicationYear "1994" @default.
- W2012634577 type Work @default.
- W2012634577 sameAs 2012634577 @default.
- W2012634577 citedByCount "22" @default.
- W2012634577 countsByYear W20126345772012 @default.
- W2012634577 countsByYear W20126345772016 @default.
- W2012634577 countsByYear W20126345772018 @default.
- W2012634577 countsByYear W20126345772021 @default.
- W2012634577 countsByYear W20126345772022 @default.
- W2012634577 crossrefType "journal-article" @default.
- W2012634577 hasAuthorship W2012634577A5014604969 @default.
- W2012634577 hasAuthorship W2012634577A5026687937 @default.
- W2012634577 hasAuthorship W2012634577A5039946998 @default.
- W2012634577 hasAuthorship W2012634577A5061633444 @default.
- W2012634577 hasBestOaLocation W20126345771 @default.
- W2012634577 hasConcept C104317684 @default.
- W2012634577 hasConcept C14036430 @default.
- W2012634577 hasConcept C166393388 @default.
- W2012634577 hasConcept C193252679 @default.
- W2012634577 hasConcept C2988562018 @default.
- W2012634577 hasConcept C54355233 @default.
- W2012634577 hasConcept C78458016 @default.
- W2012634577 hasConcept C86803240 @default.
- W2012634577 hasConcept C90132467 @default.
- W2012634577 hasConceptScore W2012634577C104317684 @default.
- W2012634577 hasConceptScore W2012634577C14036430 @default.
- W2012634577 hasConceptScore W2012634577C166393388 @default.
- W2012634577 hasConceptScore W2012634577C193252679 @default.
- W2012634577 hasConceptScore W2012634577C2988562018 @default.
- W2012634577 hasConceptScore W2012634577C54355233 @default.
- W2012634577 hasConceptScore W2012634577C78458016 @default.
- W2012634577 hasConceptScore W2012634577C86803240 @default.
- W2012634577 hasConceptScore W2012634577C90132467 @default.
- W2012634577 hasIssue "5" @default.
- W2012634577 hasLocation W20126345771 @default.
- W2012634577 hasLocation W20126345772 @default.
- W2012634577 hasOpenAccess W2012634577 @default.
- W2012634577 hasPrimaryLocation W20126345771 @default.
- W2012634577 hasRelatedWork W2039958682 @default.
- W2012634577 hasRelatedWork W2048921521 @default.
- W2012634577 hasRelatedWork W2074675159 @default.
- W2012634577 hasRelatedWork W2275101919 @default.
- W2012634577 hasRelatedWork W2626338337 @default.
- W2012634577 hasRelatedWork W3044186613 @default.
- W2012634577 hasRelatedWork W3104823851 @default.
- W2012634577 hasRelatedWork W3166248435 @default.
- W2012634577 hasRelatedWork W3209726119 @default.
- W2012634577 hasRelatedWork W4310654541 @default.
- W2012634577 hasVolume "69" @default.
- W2012634577 isParatext "false" @default.
- W2012634577 isRetracted "false" @default.
- W2012634577 magId "2012634577" @default.
- W2012634577 workType "article" @default.