FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012642713> ?p ?o ?g. }

• W2012642713 endingPage "2861" @default.
• W2012642713 startingPage "2841" @default.
• W2012642713 abstract "The aim of this study is to develop and test an intravascular positron imaging system based on a storage phosphor detector for imaging and detecting vulnerable plaques of human coronary arteries. The radiotracer F18-FDG accumulates in vulnerable plaques with inflammation of the overlying cap. The vulnerable plaques can, therefore, be imaged by recording positrons emitted from F18-FDG with a detector inserted into the artery. A prototype intravascular detector was constructed based on storage phosphor. The detector uses a flexible storage phosphor tube with 55 mm length, 2 mm diameter and 0.28 mm wall thickness. The intravascular detector is guided into the vessel using x-ray fluoroscopy and the accumulated x-ray signal must be erased prior to positron imaging. For this purpose, a light diffuser, 0.9 mm in diameter and 55 mm in length, was inserted into the detector tube. The light diffuser was connected to a laser source through a 2 m long optical fiber. The diffuser redirected the 0.38 W laser light to the inner surface of the phosphor detector to erase it. A heart phantom with 300 cm(3) volume and three coronary arteries with 3.2 mm diameter and with several plaques was constructed. FDG solution with 0.5 microCi cm(-3) activity concentration was filled in the heart and coronary arteries. The detector was inserted in a coronary artery and the signal from the plaques and surrounding background activity was recorded for 2 min. Then the phosphor detector was extracted and read out using a storage phosphor reader. The light diffuser erased the signal resulting from fluoroscopic exposure to level below that encountered during positron imaging. Vulnerable plaques with area activities higher than 1.2 nCi mm(-2) were visualized by the detector. This activity is a factor of 10-20 lower than that expected in human vulnerable plaques. The detector was able to image the internal surface of the coronary vessels with 50 mm length and 360 degrees circumference. Spatial resolution was 0.6-1.2 mm FWHM with a readout pixel resolution of 80 microm. The detector is flexible, reusable and easy to handle; it provides virtually real-time imaging. An intravascular imaging detector based on storage phosphor has shown a potential for imaging human coronary artery plaques. The detector provides the sensitivity, spatial resolution, flexibility and short imaging times necessary for clinical applications. Future research will decrease the detector diameter from 2 mm to 1 mm, and will apply the design to in vivo animal experiments." @default.
• W2012642713 created "2016-06-24" @default.
• W2012642713 creator A5001466579 @default.
• W2012642713 creator A5019242095 @default.
• W2012642713 creator A5033401017 @default.
• W2012642713 creator A5054178037 @default.
• W2012642713 creator A5083255866 @default.
• W2012642713 creator A5088677054 @default.
• W2012642713 date "2010-04-29" @default.
• W2012642713 modified "2023-09-26" @default.
• W2012642713 title "Intravascular imaging with a storage phosphor detector" @default.
• W2012642713 cites W1965694122 @default.
• W2012642713 cites W2010624495 @default.
• W2012642713 cites W2017335610 @default.
• W2012642713 cites W2017886856 @default.
• W2012642713 cites W2023801044 @default.
• W2012642713 cites W2028063382 @default.
• W2012642713 cites W2032335787 @default.
• W2012642713 cites W2039297838 @default.
• W2012642713 cites W2046836946 @default.
• W2012642713 cites W2057332419 @default.
• W2012642713 cites W2061350538 @default.
• W2012642713 cites W2075518691 @default.
• W2012642713 cites W2091992773 @default.
• W2012642713 cites W2110590841 @default.
• W2012642713 cites W2138008481 @default.
• W2012642713 cites W2148706200 @default.
• W2012642713 cites W2157388012 @default.
• W2012642713 cites W2161137920 @default.
• W2012642713 cites W2166536500 @default.
• W2012642713 doi "https://doi.org/10.1088/0031-9155/55/10/004" @default.
• W2012642713 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20427852" @default.
• W2012642713 hasPublicationYear "2010" @default.
• W2012642713 type Work @default.
• W2012642713 sameAs 2012642713 @default.
• W2012642713 citedByCount "0" @default.
• W2012642713 crossrefType "journal-article" @default.
• W2012642713 hasAuthorship W2012642713A5001466579 @default.
• W2012642713 hasAuthorship W2012642713A5019242095 @default.
• W2012642713 hasAuthorship W2012642713A5033401017 @default.
• W2012642713 hasAuthorship W2012642713A5054178037 @default.
• W2012642713 hasAuthorship W2012642713A5083255866 @default.
• W2012642713 hasAuthorship W2012642713A5088677054 @default.
• W2012642713 hasConcept C104293457 @default.
• W2012642713 hasConcept C120665830 @default.
• W2012642713 hasConcept C121332964 @default.
• W2012642713 hasConcept C124385694 @default.
• W2012642713 hasConcept C126838900 @default.
• W2012642713 hasConcept C136229726 @default.
• W2012642713 hasConcept C141071460 @default.
• W2012642713 hasConcept C192562407 @default.
• W2012642713 hasConcept C2776805002 @default.
• W2012642713 hasConcept C2776820930 @default.
• W2012642713 hasConcept C2778742706 @default.
• W2012642713 hasConcept C2780565730 @default.
• W2012642713 hasConcept C2982854487 @default.
• W2012642713 hasConcept C2989005 @default.
• W2012642713 hasConcept C49040817 @default.
• W2012642713 hasConcept C71924100 @default.
• W2012642713 hasConcept C94915269 @default.
• W2012642713 hasConceptScore W2012642713C104293457 @default.
• W2012642713 hasConceptScore W2012642713C120665830 @default.
• W2012642713 hasConceptScore W2012642713C121332964 @default.
• W2012642713 hasConceptScore W2012642713C124385694 @default.
• W2012642713 hasConceptScore W2012642713C126838900 @default.
• W2012642713 hasConceptScore W2012642713C136229726 @default.
• W2012642713 hasConceptScore W2012642713C141071460 @default.
• W2012642713 hasConceptScore W2012642713C192562407 @default.
• W2012642713 hasConceptScore W2012642713C2776805002 @default.
• W2012642713 hasConceptScore W2012642713C2776820930 @default.
• W2012642713 hasConceptScore W2012642713C2778742706 @default.
• W2012642713 hasConceptScore W2012642713C2780565730 @default.
• W2012642713 hasConceptScore W2012642713C2982854487 @default.
• W2012642713 hasConceptScore W2012642713C2989005 @default.
• W2012642713 hasConceptScore W2012642713C49040817 @default.
• W2012642713 hasConceptScore W2012642713C71924100 @default.
• W2012642713 hasConceptScore W2012642713C94915269 @default.
• W2012642713 hasIssue "10" @default.
• W2012642713 hasLocation W20126427131 @default.
• W2012642713 hasLocation W20126427132 @default.
• W2012642713 hasOpenAccess W2012642713 @default.
• W2012642713 hasPrimaryLocation W20126427131 @default.
• W2012642713 hasRelatedWork W1148977274 @default.
• W2012642713 hasRelatedWork W1966543160 @default.
• W2012642713 hasRelatedWork W1983913674 @default.
• W2012642713 hasRelatedWork W1990413604 @default.
• W2012642713 hasRelatedWork W2010441676 @default.
• W2012642713 hasRelatedWork W202062701 @default.
• W2012642713 hasRelatedWork W2025803321 @default.
• W2012642713 hasRelatedWork W2050574497 @default.
• W2012642713 hasRelatedWork W2068058056 @default.
• W2012642713 hasRelatedWork W2137897102 @default.
• W2012642713 hasRelatedWork W2170149239 @default.
• W2012642713 hasRelatedWork W2295704819 @default.
• W2012642713 hasRelatedWork W2312854493 @default.
• W2012642713 hasRelatedWork W2388074401 @default.
• W2012642713 hasRelatedWork W2390175580 @default.
• W2012642713 hasRelatedWork W2740122529 @default.

• next