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- W2012647838 abstract "The SIN4 locus encodes a global transcriptional regulator of various yeast genes. In this report, we demonstrate that loss of function mutations in SIN4 create a multi-drug hypersensitive phenotype that is independent of PDR5 mediated resistance. Thus, double sin4, pdr5 mutants are more sensitive than single mutants. Furthermore, SIN4 does not regulate the PDR5 locus. These observations establish that yeast cells have two genetically distinct pathways conferring resistance towards similar substrates. Copyright © 1999 John Wiley & Sons, Ltd." @default.
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- W2012647838 date "1999-01-30" @default.
- W2012647838 modified "2023-09-27" @default.
- W2012647838 title "APDR5 -independent pathway of multi-drug resistance regulated by theSIN4 gene product" @default.
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- W2012647838 doi "https://doi.org/10.1002/(sici)1097-0061(19990130)15:2<133::aid-yea354>3.0.co;2-v" @default.
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