FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012654564> ?p ?o ?g. }

• W2012654564 endingPage "269" @default.
• W2012654564 startingPage "257" @default.
• W2012654564 abstract "In order to begin to investigate the developmental factors influencing co-localized neurotransmitters in the central nervous system, we have studied the ontogenesis of coexisting transmitters, substance P and serotonin, in cells of the medullary raphe of the fetal mouse using double-label immunocytochemistry. The results indicate that initial detection of these neurotransmitters occurs at embryonic day 12 in non-overlapping cell populations. Substance P-like immunoreactivity is first co-localized with serotonin in cells of the caudal medullary raphe (raphe pallidus and raphe obscurus) at embryonic day 13. The percentage of serotonin cells containing substance P was estimated at embryonic day 13 and subsequent gestational ages both by double-label immunofluorescence using fluorescein- and rhodamine-conjugated secondary antibodies and also by the elution technique. Double-label immunofluorescence routinely and reliably yielded the highest proportion of co-localized cells. At embryonic day 13, 89% of serotonin cells contained substance P-like immunoreactivity. A consistently high degree of co-localization occurred throughout embryonic development (87% at postnatal day 3) and into adulthood (87%). Colchicine treatment was required at older ages to elicit these data. Unexpectedly, we found that neurons containing substance P-like immunoreactivity in the piriform cortex and in the hypothalamus transiently expressed serotonin immunoreactivity during normal ontogenesis." @default.
• W2012654564 created "2016-06-24" @default.
• W2012654564 creator A5003258955 @default.
• W2012654564 creator A5011283323 @default.
• W2012654564 date "1989-01-01" @default.
• W2012654564 modified "2023-09-25" @default.
• W2012654564 title "Ontogeny of substance P-containing neurons in relation to serotonin-containing neurons in the central nervous system of the mouse" @default.
• W2012654564 cites W1974782548 @default.
• W2012654564 cites W1976972192 @default.
• W2012654564 cites W1982385969 @default.
• W2012654564 cites W1984547809 @default.
• W2012654564 cites W1985057945 @default.
• W2012654564 cites W1987194864 @default.
• W2012654564 cites W1989015688 @default.
• W2012654564 cites W1989596698 @default.
• W2012654564 cites W1995285208 @default.
• W2012654564 cites W2000120439 @default.
• W2012654564 cites W2001834645 @default.
• W2012654564 cites W2003673307 @default.
• W2012654564 cites W2011757416 @default.
• W2012654564 cites W2014741978 @default.
• W2012654564 cites W2016469907 @default.
• W2012654564 cites W2020460680 @default.
• W2012654564 cites W2026237708 @default.
• W2012654564 cites W2027578671 @default.
• W2012654564 cites W2028301957 @default.
• W2012654564 cites W2028618631 @default.
• W2012654564 cites W2032695654 @default.
• W2012654564 cites W2038174426 @default.
• W2012654564 cites W2038189236 @default.
• W2012654564 cites W2040181384 @default.
• W2012654564 cites W2044774668 @default.
• W2012654564 cites W2053587734 @default.
• W2012654564 cites W2058009747 @default.
• W2012654564 cites W2066635530 @default.
• W2012654564 cites W2079743165 @default.
• W2012654564 cites W2082630503 @default.
• W2012654564 cites W2087558736 @default.
• W2012654564 cites W2092990835 @default.
• W2012654564 cites W2095195336 @default.
• W2012654564 cites W2101036473 @default.
• W2012654564 cites W941440561 @default.
• W2012654564 doi "https://doi.org/10.1016/0306-4522(89)90371-0" @default.
• W2012654564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2473413" @default.
• W2012654564 hasPublicationYear "1989" @default.
• W2012654564 type Work @default.
• W2012654564 sameAs 2012654564 @default.
• W2012654564 citedByCount "29" @default.
• W2012654564 crossrefType "journal-article" @default.
• W2012654564 hasAuthorship W2012654564A5003258955 @default.
• W2012654564 hasAuthorship W2012654564A5011283323 @default.
• W2012654564 hasConcept C104317684 @default.
• W2012654564 hasConcept C118303440 @default.
• W2012654564 hasConcept C126322002 @default.
• W2012654564 hasConcept C134018914 @default.
• W2012654564 hasConcept C145103041 @default.
• W2012654564 hasConcept C159654299 @default.
• W2012654564 hasConcept C170493617 @default.
• W2012654564 hasConcept C203014093 @default.
• W2012654564 hasConcept C2775864247 @default.
• W2012654564 hasConcept C2776533618 @default.
• W2012654564 hasConcept C2777615928 @default.
• W2012654564 hasConcept C2777865548 @default.
• W2012654564 hasConcept C2778236600 @default.
• W2012654564 hasConcept C35866371 @default.
• W2012654564 hasConcept C37000724 @default.
• W2012654564 hasConcept C37291498 @default.
• W2012654564 hasConcept C529278444 @default.
• W2012654564 hasConcept C55493867 @default.
• W2012654564 hasConcept C71924100 @default.
• W2012654564 hasConcept C86803240 @default.
• W2012654564 hasConceptScore W2012654564C104317684 @default.
• W2012654564 hasConceptScore W2012654564C118303440 @default.
• W2012654564 hasConceptScore W2012654564C126322002 @default.
• W2012654564 hasConceptScore W2012654564C134018914 @default.
• W2012654564 hasConceptScore W2012654564C145103041 @default.
• W2012654564 hasConceptScore W2012654564C159654299 @default.
• W2012654564 hasConceptScore W2012654564C170493617 @default.
• W2012654564 hasConceptScore W2012654564C203014093 @default.
• W2012654564 hasConceptScore W2012654564C2775864247 @default.
• W2012654564 hasConceptScore W2012654564C2776533618 @default.
• W2012654564 hasConceptScore W2012654564C2777615928 @default.
• W2012654564 hasConceptScore W2012654564C2777865548 @default.
• W2012654564 hasConceptScore W2012654564C2778236600 @default.
• W2012654564 hasConceptScore W2012654564C35866371 @default.
• W2012654564 hasConceptScore W2012654564C37000724 @default.
• W2012654564 hasConceptScore W2012654564C37291498 @default.
• W2012654564 hasConceptScore W2012654564C529278444 @default.
• W2012654564 hasConceptScore W2012654564C55493867 @default.
• W2012654564 hasConceptScore W2012654564C71924100 @default.
• W2012654564 hasConceptScore W2012654564C86803240 @default.
• W2012654564 hasIssue "1" @default.
• W2012654564 hasLocation W20126545641 @default.
• W2012654564 hasLocation W20126545642 @default.
• W2012654564 hasOpenAccess W2012654564 @default.
• W2012654564 hasPrimaryLocation W20126545641 @default.
• W2012654564 hasRelatedWork W1984841954 @default.
• W2012654564 hasRelatedWork W2018661737 @default.

• next