FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012663711> ?p ?o ?g. }

• W2012663711 endingPage "188" @default.
• W2012663711 startingPage "179" @default.
• W2012663711 abstract "Six types of plasmid-mediated carbenicillinases can be distinguished on the basis of their substrate profiles, molecular mass isoelectrić values and immunological properties. As yet, no structural classification has been attempted for these enzymes at the molecular level. We have isolated the PSE-4 structural gene responsible for carbenicillinase production in Pseudomonas aeruginosa strain Dalgleish and studied its expression in E. coli. A detailed physical map of the cloned fragment and the construction of deletion mutants permitted the precise localization of the PSE-4 structural gene. Various restriction endonuclease fragments known to be flanking or internal to the PSE-4 bla gene were used as DNA probes and tested for homologous sequences in other β-lactamase genes. A collection of three restriction fragment probes internal or delimiting the PSE-4 structural gene were hybridized with purified plasmid DNA coding for 18 other β-lactamases. Under high stringency conditions, only the PSE-1, CARB-3 and CARB-4 genes cross-hybridized with PSE-4; while one of the probes tested hybridized solely with CARB-3. Further analysis indicated that the PSE-1, PSE-4, CARB-3 and CARB-4 bla genes are related and could presumably have evolved from a common progenitor." @default.
• W2012663711 created "2016-06-24" @default.
• W2012663711 creator A5014228992 @default.
• W2012663711 creator A5056962550 @default.
• W2012663711 creator A5058001103 @default.
• W2012663711 creator A5074847364 @default.
• W2012663711 date "1989-06-01" @default.
• W2012663711 modified "2023-09-26" @default.
• W2012663711 title "Development of gene probes and evolutionary relationships of the PSE-4 bla gene to plasmid-mediated β-lactamases of gram-negative bacteria" @default.
• W2012663711 cites W114285225 @default.
• W2012663711 cites W1541473088 @default.
• W2012663711 cites W1655656815 @default.
• W2012663711 cites W1912451872 @default.
• W2012663711 cites W1915783526 @default.
• W2012663711 cites W1927972199 @default.
• W2012663711 cites W1970599877 @default.
• W2012663711 cites W1978058211 @default.
• W2012663711 cites W1987634568 @default.
• W2012663711 cites W1994256566 @default.
• W2012663711 cites W1999544696 @default.
• W2012663711 cites W2017767089 @default.
• W2012663711 cites W2018712142 @default.
• W2012663711 cites W2019696290 @default.
• W2012663711 cites W2029987769 @default.
• W2012663711 cites W2030502750 @default.
• W2012663711 cites W2036903205 @default.
• W2012663711 cites W2048926294 @default.
• W2012663711 cites W2049413142 @default.
• W2012663711 cites W2050499271 @default.
• W2012663711 cites W2051615505 @default.
• W2012663711 cites W2051687036 @default.
• W2012663711 cites W2053113679 @default.
• W2012663711 cites W2053199282 @default.
• W2012663711 cites W2072239659 @default.
• W2012663711 cites W2077308230 @default.
• W2012663711 cites W2084966633 @default.
• W2012663711 cites W2093710523 @default.
• W2012663711 cites W2099369153 @default.
• W2012663711 cites W2109068357 @default.
• W2012663711 cites W2112545344 @default.
• W2012663711 cites W2132481027 @default.
• W2012663711 cites W2141653906 @default.
• W2012663711 cites W2146174878 @default.
• W2012663711 cites W2150260344 @default.
• W2012663711 cites W37464992 @default.
• W2012663711 doi "https://doi.org/10.1016/0890-8508(89)90028-5" @default.
• W2012663711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2788807" @default.
• W2012663711 hasPublicationYear "1989" @default.
• W2012663711 type Work @default.
• W2012663711 sameAs 2012663711 @default.
• W2012663711 citedByCount "4" @default.
• W2012663711 crossrefType "journal-article" @default.
• W2012663711 hasAuthorship W2012663711A5014228992 @default.
• W2012663711 hasAuthorship W2012663711A5056962550 @default.
• W2012663711 hasAuthorship W2012663711A5058001103 @default.
• W2012663711 hasAuthorship W2012663711A5074847364 @default.
• W2012663711 hasConcept C104317684 @default.
• W2012663711 hasConcept C128319531 @default.
• W2012663711 hasConcept C143065580 @default.
• W2012663711 hasConcept C150194340 @default.
• W2012663711 hasConcept C153911025 @default.
• W2012663711 hasConcept C170673058 @default.
• W2012663711 hasConcept C19924922 @default.
• W2012663711 hasConcept C22744801 @default.
• W2012663711 hasConcept C54355233 @default.
• W2012663711 hasConcept C5527404 @default.
• W2012663711 hasConcept C552990157 @default.
• W2012663711 hasConcept C86803240 @default.
• W2012663711 hasConceptScore W2012663711C104317684 @default.
• W2012663711 hasConceptScore W2012663711C128319531 @default.
• W2012663711 hasConceptScore W2012663711C143065580 @default.
• W2012663711 hasConceptScore W2012663711C150194340 @default.
• W2012663711 hasConceptScore W2012663711C153911025 @default.
• W2012663711 hasConceptScore W2012663711C170673058 @default.
• W2012663711 hasConceptScore W2012663711C19924922 @default.
• W2012663711 hasConceptScore W2012663711C22744801 @default.
• W2012663711 hasConceptScore W2012663711C54355233 @default.
• W2012663711 hasConceptScore W2012663711C5527404 @default.
• W2012663711 hasConceptScore W2012663711C552990157 @default.
• W2012663711 hasConceptScore W2012663711C86803240 @default.
• W2012663711 hasIssue "2" @default.
• W2012663711 hasLocation W20126637111 @default.
• W2012663711 hasLocation W20126637112 @default.
• W2012663711 hasOpenAccess W2012663711 @default.
• W2012663711 hasPrimaryLocation W20126637111 @default.
• W2012663711 hasRelatedWork W2033822211 @default.
• W2012663711 hasRelatedWork W2052903221 @default.
• W2012663711 hasRelatedWork W2059875550 @default.
• W2012663711 hasRelatedWork W2082400949 @default.
• W2012663711 hasRelatedWork W2084399376 @default.
• W2012663711 hasRelatedWork W2110037457 @default.
• W2012663711 hasRelatedWork W2129411648 @default.
• W2012663711 hasRelatedWork W2163973619 @default.
• W2012663711 hasRelatedWork W2376603524 @default.
• W2012663711 hasRelatedWork W2416356849 @default.
• W2012663711 hasVolume "3" @default.
• W2012663711 isParatext "false" @default.
• W2012663711 isRetracted "false" @default.

• next