FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012668389> ?p ?o ?g. }

• W2012668389 endingPage "417" @default.
• W2012668389 startingPage "409" @default.
• W2012668389 abstract "The Hering-Breuer reflex is one of the fundamental respiratory reflexes and is mediated by second-order relay neurons of the slowly adapting lung stretch receptors. These neurons, which are called pump cells, are located in the nucleus tractus solitarii and include a population of inhibitory neurons. We aimed to determine which transmitter, GABA or glycine, the inhibitory pump cells use. In addition, we examined whether or not second-order relay neurons of the rapidly-adapting lung stretch receptors (RAR-cells), whose excitatory or inhibitory nature is not known, use these inhibitory neurotransmitters. In Nembutal-anesthetized, neuromuscularly blocked and artificially ventilated rats, we labeled pump cells (n=33) and RAR-cells (n=26) with Neurobiotin and processed the tissues for detection of mRNA encoding either glutamic acid decarboxylase isoform 67 (GAD67) or glycine transporter 2 (GLYT2) using in situ hybridization. The pump cells were located in the interstitial nucleus and its vicinity and the RAR-cells in the commissural subnucleus. The majority (64%) of the pump cells examined for GAD67 mRNA and many (26%) of the pump cells examined for GLYT2 mRNA expressed respective mRNAs. Of the eight pump cells in which both mRNAs were double-detected, three expressed both mRNAs and one expressed GAD67 mRNA but not GLYT2 mRNA, the other four expressing neither mRNAs. On the other hand, RAR-cells expressed neither GAD67 mRNA nor GLYT2 mRNA. The results suggest that the inhibitory pump cells are basically GABAergic and some of them may corelease GABA and glycine, and that RAR-cells are neither GABAergic nor glycinergic. These findings expand our understanding of the networks of lung receptor-mediated reflexes including the Hering-Breuer reflex." @default.
• W2012668389 created "2016-06-24" @default.
• W2012668389 creator A5025198164 @default.
• W2012668389 creator A5033873918 @default.
• W2012668389 date "2004-01-01" @default.
• W2012668389 modified "2023-09-24" @default.
• W2012668389 title "GABA, in some cases together with glycine, is used as the inhibitory transmitter by pump cells in the Hering-Breuer reflex pathway of the rat" @default.
• W2012668389 cites W1504117327 @default.
• W2012668389 cites W1556811685 @default.
• W2012668389 cites W1578249395 @default.
• W2012668389 cites W1600455132 @default.
• W2012668389 cites W1904057448 @default.
• W2012668389 cites W1920463507 @default.
• W2012668389 cites W1939572055 @default.
• W2012668389 cites W1952039887 @default.
• W2012668389 cites W1967708176 @default.
• W2012668389 cites W1974009966 @default.
• W2012668389 cites W1974011993 @default.
• W2012668389 cites W1978488098 @default.
• W2012668389 cites W1990189870 @default.
• W2012668389 cites W2005405942 @default.
• W2012668389 cites W2008026075 @default.
• W2012668389 cites W2008645590 @default.
• W2012668389 cites W2009416783 @default.
• W2012668389 cites W2011362828 @default.
• W2012668389 cites W2014137821 @default.
• W2012668389 cites W2017776111 @default.
• W2012668389 cites W2018760402 @default.
• W2012668389 cites W2019724129 @default.
• W2012668389 cites W2020063999 @default.
• W2012668389 cites W2022062405 @default.
• W2012668389 cites W2027536438 @default.
• W2012668389 cites W2037857436 @default.
• W2012668389 cites W2042879230 @default.
• W2012668389 cites W2046926887 @default.
• W2012668389 cites W2048662846 @default.
• W2012668389 cites W2049879893 @default.
• W2012668389 cites W2049978992 @default.
• W2012668389 cites W2053302747 @default.
• W2012668389 cites W2054758021 @default.
• W2012668389 cites W2055800640 @default.
• W2012668389 cites W2063640181 @default.
• W2012668389 cites W2066799934 @default.
• W2012668389 cites W2071814459 @default.
• W2012668389 cites W2074361827 @default.
• W2012668389 cites W2074596357 @default.
• W2012668389 cites W2083081147 @default.
• W2012668389 cites W2084414231 @default.
• W2012668389 cites W2086248309 @default.
• W2012668389 cites W2089244845 @default.
• W2012668389 cites W2092246706 @default.
• W2012668389 cites W2093465585 @default.
• W2012668389 cites W2093840035 @default.
• W2012668389 cites W2118064464 @default.
• W2012668389 cites W2131623826 @default.
• W2012668389 cites W2138175169 @default.
• W2012668389 cites W2143019295 @default.
• W2012668389 cites W2148055538 @default.
• W2012668389 cites W2149131718 @default.
• W2012668389 cites W2219548386 @default.
• W2012668389 cites W2245630575 @default.
• W2012668389 cites W2324830287 @default.
• W2012668389 cites W2429752171 @default.
• W2012668389 cites W4242347580 @default.
• W2012668389 doi "https://doi.org/10.1016/j.neuroscience.2004.05.032" @default.
• W2012668389 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15262331" @default.
• W2012668389 hasPublicationYear "2004" @default.
• W2012668389 type Work @default.
• W2012668389 sameAs 2012668389 @default.
• W2012668389 citedByCount "56" @default.
• W2012668389 countsByYear W20126683892012 @default.
• W2012668389 countsByYear W20126683892013 @default.
• W2012668389 countsByYear W20126683892014 @default.
• W2012668389 countsByYear W20126683892015 @default.
• W2012668389 countsByYear W20126683892016 @default.
• W2012668389 countsByYear W20126683892017 @default.
• W2012668389 countsByYear W20126683892018 @default.
• W2012668389 countsByYear W20126683892019 @default.
• W2012668389 countsByYear W20126683892020 @default.
• W2012668389 countsByYear W20126683892021 @default.
• W2012668389 countsByYear W20126683892022 @default.
• W2012668389 countsByYear W20126683892023 @default.
• W2012668389 crossrefType "journal-article" @default.
• W2012668389 hasAuthorship W2012668389A5025198164 @default.
• W2012668389 hasAuthorship W2012668389A5033873918 @default.
• W2012668389 hasConcept C104317684 @default.
• W2012668389 hasConcept C105580179 @default.
• W2012668389 hasConcept C169760540 @default.
• W2012668389 hasConcept C170493617 @default.
• W2012668389 hasConcept C17077164 @default.
• W2012668389 hasConcept C181199279 @default.
• W2012668389 hasConcept C2777756961 @default.
• W2012668389 hasConcept C2779177108 @default.
• W2012668389 hasConcept C2908647359 @default.
• W2012668389 hasConcept C35599011 @default.
• W2012668389 hasConcept C515207424 @default.
• W2012668389 hasConcept C55493867 @default.
• W2012668389 hasConcept C61174792 @default.

• next