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- W2012680003 abstract "Purpose of review To examine the role of fluid therapy in the pathogenesis of severe sepsis and septic shock. The type, composition, titration, management strategies and complications of fluid administration will be examined in respect to outcomes. Recent findings Fluids have a critical role in the pathogenesis and treatment of early resuscitation of severe sepsis and septic shock. Summary Although this pathogenesis is evolving, early titrated fluid administration modulates inflammation, improves microvascular perfusion, impacts organ function and outcome. Fluid administration has limited impact on tissue perfusion during the later stages of sepsis and excess fluid is deleterious to outcome. The type of fluid solution does not seem to influence these observations." @default.
- W2012680003 created "2016-06-24" @default.
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- W2012680003 date "2010-08-01" @default.
- W2012680003 modified "2023-10-14" @default.
- W2012680003 title "Fluid therapy in septic shock" @default.
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- W2012680003 doi "https://doi.org/10.1097/mcc.0b013e32833be8b3" @default.
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