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• W201274012 endingPage "833" @default.
• W201274012 startingPage "819" @default.
• W201274012 abstract "Immune Thrombocytopenia (ITP) is an antibody-mediated condition wherein autoimmune platelet destruction leads to low platelet counts and variable degrees of bleeding. It is a heterogeneous condition. Several mechanisms have been implicated in its pathogenesis, involving B-cells, T-cells and immunomodulatory cytokines, and there is great variation among patients in their disease severity and response to individual treatments. Recently, novel therapies have been developed to inhibit the immune platelet destruction and also to boost platelet production by megakaryocytes via thrombopoietin (TPO) receptor stimulation. This chapter outlines the pathological and clinical aspects of ITP and suggests current management options based on recently published consensus guidelines." @default.
• W201274012 created "2016-06-24" @default.
• W201274012 creator A5053302921 @default.
• W201274012 creator A5062688748 @default.
• W201274012 date "2013-01-01" @default.
• W201274012 modified "2023-10-14" @default.
• W201274012 title "Immune Thrombocytopenia (ITP)" @default.
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