FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012776611> ?p ?o ?g. }

• W2012776611 endingPage "153" @default.
• W2012776611 startingPage "147" @default.
• W2012776611 abstract "Twenty six endocrine tumors of the pancreas and 19 carcinoids of the intestinal tract were studied with immunocyto-chemical staining for p53 and proliferating cell nuclear antigen (PCNA) to detect any correlation between PCNA and p53 immunostaining. PCNA immunostaining is some-what variable in endocrine tumors of the pancreas whereas p53 overexpression was detected in one out of eight insulinomas (12.5%), four out of eight gastrinomas (50%) and none of two glucagonomas, six PPomas and two nonfunctioning tumors. In 19 intestinal carcinoids, two of eight small-intestinal carcinoids (25%) were positive for p53 whereas five appendiceal and two colonic carcinoids were negative for p53. It was concluded that: 1.PCNA staining is variable with no clear distinction between benign and malignant endocrine tumors of the pancreas and intestinal carcinoids, although positive PCNA staining may assess growth fraction of tumors; 2.p53 overexpression is relatively rare both in endocrine tumors of the pancreas (one out of 18 non-gastrinomas) and intestinal carcinoids, except for gastrinomas, in which 50% were positive for p53; and 3.non-neoplastic islet cells are positive for p53. Twenty six endocrine tumors of the pancreas and 19 carcinoids of the intestinal tract were studied with immunocyto-chemical staining for p53 and proliferating cell nuclear antigen (PCNA) to detect any correlation between PCNA and p53 immunostaining. PCNA immunostaining is some-what variable in endocrine tumors of the pancreas whereas p53 overexpression was detected in one out of eight insulinomas (12.5%), four out of eight gastrinomas (50%) and none of two glucagonomas, six PPomas and two nonfunctioning tumors. In 19 intestinal carcinoids, two of eight small-intestinal carcinoids (25%) were positive for p53 whereas five appendiceal and two colonic carcinoids were negative for p53. It was concluded that: 1.PCNA staining is variable with no clear distinction between benign and malignant endocrine tumors of the pancreas and intestinal carcinoids, although positive PCNA staining may assess growth fraction of tumors; 2.p53 overexpression is relatively rare both in endocrine tumors of the pancreas (one out of 18 non-gastrinomas) and intestinal carcinoids, except for gastrinomas, in which 50% were positive for p53; and 3.non-neoplastic islet cells are positive for p53." @default.
• W2012776611 created "2016-06-24" @default.
• W2012776611 creator A5067805022 @default.
• W2012776611 date "1997-01-01" @default.
• W2012776611 modified "2023-09-26" @default.
• W2012776611 title "p53 And proliferating cell nuclear antigen in endocrine tumors of pancreas and intestinal carcinoids" @default.
• W2012776611 cites W1947531295 @default.
• W2012776611 cites W1978414069 @default.
• W2012776611 cites W2008301561 @default.
• W2012776611 cites W2014549694 @default.
• W2012776611 cites W2020491883 @default.
• W2012776611 cites W2029057177 @default.
• W2012776611 cites W2037697600 @default.
• W2012776611 cites W2040876807 @default.
• W2012776611 cites W2042316019 @default.
• W2012776611 cites W2047075593 @default.
• W2012776611 cites W2094471078 @default.
• W2012776611 cites W2107288032 @default.
• W2012776611 cites W2111703821 @default.
• W2012776611 cites W2121328511 @default.
• W2012776611 cites W2167118789 @default.
• W2012776611 doi "https://doi.org/10.1080/00313029700169774" @default.
• W2012776611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9213333" @default.
• W2012776611 hasPublicationYear "1997" @default.
• W2012776611 type Work @default.
• W2012776611 sameAs 2012776611 @default.
• W2012776611 citedByCount "9" @default.
• W2012776611 crossrefType "journal-article" @default.
• W2012776611 hasAuthorship W2012776611A5067805022 @default.
• W2012776611 hasConcept C134018914 @default.
• W2012776611 hasConcept C142724271 @default.
• W2012776611 hasConcept C204232928 @default.
• W2012776611 hasConcept C2778764654 @default.
• W2012776611 hasConcept C34688535 @default.
• W2012776611 hasConcept C4224716 @default.
• W2012776611 hasConcept C46699223 @default.
• W2012776611 hasConcept C71315377 @default.
• W2012776611 hasConcept C71924100 @default.
• W2012776611 hasConcept C77231918 @default.
• W2012776611 hasConcept C86803240 @default.
• W2012776611 hasConceptScore W2012776611C134018914 @default.
• W2012776611 hasConceptScore W2012776611C142724271 @default.
• W2012776611 hasConceptScore W2012776611C204232928 @default.
• W2012776611 hasConceptScore W2012776611C2778764654 @default.
• W2012776611 hasConceptScore W2012776611C34688535 @default.
• W2012776611 hasConceptScore W2012776611C4224716 @default.
• W2012776611 hasConceptScore W2012776611C46699223 @default.
• W2012776611 hasConceptScore W2012776611C71315377 @default.
• W2012776611 hasConceptScore W2012776611C71924100 @default.
• W2012776611 hasConceptScore W2012776611C77231918 @default.
• W2012776611 hasConceptScore W2012776611C86803240 @default.
• W2012776611 hasIssue "2" @default.
• W2012776611 hasLocation W20127766111 @default.
• W2012776611 hasLocation W20127766112 @default.
• W2012776611 hasOpenAccess W2012776611 @default.
• W2012776611 hasPrimaryLocation W20127766111 @default.
• W2012776611 hasRelatedWork W1969067203 @default.
• W2012776611 hasRelatedWork W2012776611 @default.
• W2012776611 hasRelatedWork W2058538432 @default.
• W2012776611 hasRelatedWork W2275481208 @default.
• W2012776611 hasRelatedWork W2363644609 @default.
• W2012776611 hasRelatedWork W2407384325 @default.
• W2012776611 hasRelatedWork W2410238242 @default.
• W2012776611 hasRelatedWork W2413419393 @default.
• W2012776611 hasRelatedWork W284332429 @default.
• W2012776611 hasRelatedWork W68975081 @default.
• W2012776611 hasVolume "29" @default.
• W2012776611 isParatext "false" @default.
• W2012776611 isRetracted "false" @default.
• W2012776611 magId "2012776611" @default.
• W2012776611 workType "article" @default.