FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012803400> ?p ?o ?g. }

• W2012803400 endingPage "1228" @default.
• W2012803400 startingPage "1223" @default.
• W2012803400 abstract "To examine the effect of interleukin-1 (IL-1) on CRF and POMC gene expression, recombinant human IL-1α and β were ip injected in rats. The plasma ACTH level showed a dose-related increase at 2 h after the injection of 0.5 and 2 μg IL-1α and -β, and also showed a sustained increase from 1 h until 5 h after the injection of 2 μg of IL-1β. CRF contents in the medial basal hypothalamus and ACTH contents in the anterior pituitary (AP) decreased at 2 h after the injection of 2 μg of IL-1α and -β, and such decreased levels were maintained until 5 h after the injection of 2 μg of IL-1β. The levels of CRF mRNA in the hypothalamus and POMC mRNA in AP significantly increased 3 h after the injection of 2 μg IL-1α and β, and these levels were still higher at 5 h after the injection of 2 μg of IL-1β compared with those of the control. There was no significant change in the ACTH content and POMC mRNA levels in the intermediate-posterior pituitary or the hypothalamus or in the CRF contents and CRF mRNA levels in the cerebral cortex. These results indicate that acute administration of IL-1α and -β stimulates gene expression of hypothalamic CRF and CRF release, which causes the stimulation of ACTH release and POMC gene expression in AP. (Endocrinology126: 1223–1228, 1990)" @default.
• W2012803400 created "2016-06-24" @default.
• W2012803400 creator A5008734901 @default.
• W2012803400 creator A5030293363 @default.
• W2012803400 creator A5053304351 @default.
• W2012803400 creator A5054636847 @default.
• W2012803400 creator A5058927732 @default.
• W2012803400 creator A5070200499 @default.
• W2012803400 date "1990-02-01" @default.
• W2012803400 modified "2023-10-15" @default.
• W2012803400 title "Interleukin-1 Stimulates Corticotropin-Releasing Factor Gene Expression in Rat Hypothalamus*" @default.
• W2012803400 cites W1966210609 @default.
• W2012803400 cites W1972557015 @default.
• W2012803400 cites W1974457826 @default.
• W2012803400 cites W1978255802 @default.
• W2012803400 cites W1989585054 @default.
• W2012803400 cites W1998785835 @default.
• W2012803400 cites W2000956334 @default.
• W2012803400 cites W2004652754 @default.
• W2012803400 cites W2016311952 @default.
• W2012803400 cites W2027057043 @default.
• W2012803400 cites W2028082957 @default.
• W2012803400 cites W2029027714 @default.
• W2012803400 cites W2035072797 @default.
• W2012803400 cites W2038297164 @default.
• W2012803400 cites W2045605935 @default.
• W2012803400 cites W2051488242 @default.
• W2012803400 cites W2053450186 @default.
• W2012803400 cites W2062444650 @default.
• W2012803400 cites W2066947713 @default.
• W2012803400 cites W2070793461 @default.
• W2012803400 cites W2142800802 @default.
• W2012803400 cites W2145890122 @default.
• W2012803400 cites W2220741707 @default.
• W2012803400 cites W291386200 @default.
• W2012803400 cites W2980494848 @default.
• W2012803400 doi "https://doi.org/10.1210/endo-126-2-1223" @default.
• W2012803400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2153522" @default.
• W2012803400 hasPublicationYear "1990" @default.
• W2012803400 type Work @default.
• W2012803400 sameAs 2012803400 @default.
• W2012803400 citedByCount "179" @default.
• W2012803400 countsByYear W20128034002012 @default.
• W2012803400 countsByYear W20128034002014 @default.
• W2012803400 countsByYear W20128034002017 @default.
• W2012803400 countsByYear W20128034002018 @default.
• W2012803400 countsByYear W20128034002019 @default.
• W2012803400 crossrefType "journal-article" @default.
• W2012803400 hasAuthorship W2012803400A5008734901 @default.
• W2012803400 hasAuthorship W2012803400A5030293363 @default.
• W2012803400 hasAuthorship W2012803400A5053304351 @default.
• W2012803400 hasAuthorship W2012803400A5054636847 @default.
• W2012803400 hasAuthorship W2012803400A5058927732 @default.
• W2012803400 hasAuthorship W2012803400A5070200499 @default.
• W2012803400 hasConcept C104317684 @default.
• W2012803400 hasConcept C105580179 @default.
• W2012803400 hasConcept C126322002 @default.
• W2012803400 hasConcept C134018914 @default.
• W2012803400 hasConcept C150194340 @default.
• W2012803400 hasConcept C185592680 @default.
• W2012803400 hasConcept C24998067 @default.
• W2012803400 hasConcept C2777003273 @default.
• W2012803400 hasConcept C2777658017 @default.
• W2012803400 hasConcept C2778024521 @default.
• W2012803400 hasConcept C2778458438 @default.
• W2012803400 hasConcept C2779029589 @default.
• W2012803400 hasConcept C2779306644 @default.
• W2012803400 hasConcept C55493867 @default.
• W2012803400 hasConcept C71315377 @default.
• W2012803400 hasConcept C71924100 @default.
• W2012803400 hasConcept C86803240 @default.
• W2012803400 hasConceptScore W2012803400C104317684 @default.
• W2012803400 hasConceptScore W2012803400C105580179 @default.
• W2012803400 hasConceptScore W2012803400C126322002 @default.
• W2012803400 hasConceptScore W2012803400C134018914 @default.
• W2012803400 hasConceptScore W2012803400C150194340 @default.
• W2012803400 hasConceptScore W2012803400C185592680 @default.
• W2012803400 hasConceptScore W2012803400C24998067 @default.
• W2012803400 hasConceptScore W2012803400C2777003273 @default.
• W2012803400 hasConceptScore W2012803400C2777658017 @default.
• W2012803400 hasConceptScore W2012803400C2778024521 @default.
• W2012803400 hasConceptScore W2012803400C2778458438 @default.
• W2012803400 hasConceptScore W2012803400C2779029589 @default.
• W2012803400 hasConceptScore W2012803400C2779306644 @default.
• W2012803400 hasConceptScore W2012803400C55493867 @default.
• W2012803400 hasConceptScore W2012803400C71315377 @default.
• W2012803400 hasConceptScore W2012803400C71924100 @default.
• W2012803400 hasConceptScore W2012803400C86803240 @default.
• W2012803400 hasIssue "2" @default.
• W2012803400 hasLocation W20128034001 @default.
• W2012803400 hasLocation W20128034002 @default.
• W2012803400 hasOpenAccess W2012803400 @default.
• W2012803400 hasPrimaryLocation W20128034001 @default.
• W2012803400 hasRelatedWork W2001798783 @default.
• W2012803400 hasRelatedWork W2003493199 @default.
• W2012803400 hasRelatedWork W2027251682 @default.
• W2012803400 hasRelatedWork W2069566015 @default.
• W2012803400 hasRelatedWork W2093874651 @default.

• next