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- W2012805969 abstract "T. Sugahara , T. Takahashi , S. Yamaya and A. Ohsaka . Vascular permeability increase by α-toxin (phospholipase C) of Clostridium perfringens . Toxicon 15, 81–87, 1977.—Highly purified α-toxin increased the vascular permeability in guinea-pig skin. This vascular permeability-increasing activity reached a minimum value at around 70°C but heating at higher temperatures inactivated it to a lesser extent. The same anomaly in heat inactivation was observed with the phospholipase C activity possessed by the toxin. By subjecting the purified toxin to isoelectric focusing, four molecular forms were isolated, all of which were associated with both vascular permeability-increasing and enzymatic activities. These results clearly demonstrated the identity of the factor responsible for the vascular permeability-increasing activity with α-toxin." @default.
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- W2012805969 title "Vascular permeability increase by α-toxin (phospholipase C) of Clostridium perfringens" @default.
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- W2012805969 doi "https://doi.org/10.1016/0041-0101(77)90074-5" @default.
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