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- W2012809743 abstract "Dizziness or vertigo is a common symptom in the elderly. Previous studies suggest that orthostatic dysregulation reflected by autonomic imbalance is related to the occurrence of dizziness or vertigo. We evaluated autonomic function in patients with sudden onset dizziness or vertigo who were hospitalized. Subjects were 25 patients (age 77±9 years, 7 men and 18 women) and eight normal subjects (age 72±4 years, 3 men and 5 women). After supine rest, active standing was requested, followed by glucose tolerance tests (OGTT). Sixty minutes after oral ingestion of 75 g glucose, active standing was repeated. We measured blood pressure (BP) and heart rate (HR) and obtained plasma noradrenaline (NA) and arginine vasopressin (AVP) levels before and after the first standing. In patients, BP increased with standing and decreased with OGTT. Ten patients (1 man and 9 women) had more than 20 mm Hg increase of BP on standing (orthostatic hypertension; OHT). The patients in this group were older than the patients without OHT, and had a higher baseline NA, a larger NA increase and no AVP increase during standing. They also had no increase in HR with OGTT despite a decrease in BP." @default.
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- W2012809743 date "2006-12-01" @default.
- W2012809743 modified "2023-09-27" @default.
- W2012809743 title "Orthostatic hypertension in old people with dizziness or vertigo" @default.
- W2012809743 doi "https://doi.org/10.1016/j.autneu.2006.08.019" @default.
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