Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012809928> ?p ?o ?g. }
- W2012809928 endingPage "174" @default.
- W2012809928 startingPage "167" @default.
- W2012809928 abstract "To evaluate the clinical significance of the expression of epidermal growth factor receptor (EGFr) in oral squamous cell carcinoma (SCC), 100 formalin-fixed, paraffin-embedded cases of this tumour and ten samples of normal oral mucosa were immunostained with a monoclonal anti-EGFr antibody using an immunoalkaline phosphatase (APAAP) technique. EGFr immunoreactivity was detected in 36 of 100 tumours and in all samples of normal mucosa. Tumour cells demonstrated distinct membrane staining in 14 cases and predominantly cytoplasmic staining in 22 additional cases. EGFr was exclusively localized on the cell membrane of normal epithelial cells. Kaplan–Meyer survival curves and Cox proportional hazard regression models were used to assess overall survival and disease-free survival. A significant positive correlation was shown between EGFr membranous immunoreactivity and prolonged survival, in both univariate and multivariate analyses. Accordingly, patients with oral SCC showing down-regulated expression of membranous EGFr, who are more likely to suffer recurrence and death, should be strictly followed up and possibly treated with more aggressive therapeutic regimens. © 1998 John Wiley & Sons, Ltd." @default.
- W2012809928 created "2016-06-24" @default.
- W2012809928 creator A5025327353 @default.
- W2012809928 creator A5074106135 @default.
- W2012809928 creator A5088697304 @default.
- W2012809928 date "1998-06-01" @default.
- W2012809928 modified "2023-09-24" @default.
- W2012809928 title "Prognostic implications of epidermal growth factor receptor immunoreactivity in squamous cell carcinoma of the oral mucosa" @default.
- W2012809928 cites W1968013329 @default.
- W2012809928 cites W1968808140 @default.
- W2012809928 cites W1969888740 @default.
- W2012809928 cites W1974814894 @default.
- W2012809928 cites W1975851228 @default.
- W2012809928 cites W1979040485 @default.
- W2012809928 cites W1987375161 @default.
- W2012809928 cites W1990632557 @default.
- W2012809928 cites W2005136679 @default.
- W2012809928 cites W2010489316 @default.
- W2012809928 cites W2015254793 @default.
- W2012809928 cites W2020109108 @default.
- W2012809928 cites W2020494463 @default.
- W2012809928 cites W2020583055 @default.
- W2012809928 cites W2023711780 @default.
- W2012809928 cites W2033584179 @default.
- W2012809928 cites W2034281671 @default.
- W2012809928 cites W2034348985 @default.
- W2012809928 cites W2039106539 @default.
- W2012809928 cites W2040883652 @default.
- W2012809928 cites W2055065654 @default.
- W2012809928 cites W2055961110 @default.
- W2012809928 cites W2062468721 @default.
- W2012809928 cites W2069457615 @default.
- W2012809928 cites W2074624949 @default.
- W2012809928 cites W2077369475 @default.
- W2012809928 cites W2078506318 @default.
- W2012809928 cites W2082601735 @default.
- W2012809928 cites W2094724880 @default.
- W2012809928 cites W2109296534 @default.
- W2012809928 cites W2133590033 @default.
- W2012809928 cites W2136989953 @default.
- W2012809928 cites W2157838504 @default.
- W2012809928 cites W2165305811 @default.
- W2012809928 cites W2172288671 @default.
- W2012809928 cites W2325631775 @default.
- W2012809928 doi "https://doi.org/10.1002/(sici)1096-9896(199806)185:2<167::aid-path70>3.0.co;2-e" @default.
- W2012809928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9713343" @default.
- W2012809928 hasPublicationYear "1998" @default.
- W2012809928 type Work @default.
- W2012809928 sameAs 2012809928 @default.
- W2012809928 citedByCount "39" @default.
- W2012809928 countsByYear W20128099282012 @default.
- W2012809928 countsByYear W20128099282013 @default.
- W2012809928 countsByYear W20128099282014 @default.
- W2012809928 countsByYear W20128099282015 @default.
- W2012809928 countsByYear W20128099282016 @default.
- W2012809928 countsByYear W20128099282017 @default.
- W2012809928 countsByYear W20128099282019 @default.
- W2012809928 countsByYear W20128099282020 @default.
- W2012809928 countsByYear W20128099282021 @default.
- W2012809928 countsByYear W20128099282023 @default.
- W2012809928 crossrefType "journal-article" @default.
- W2012809928 hasAuthorship W2012809928A5025327353 @default.
- W2012809928 hasAuthorship W2012809928A5074106135 @default.
- W2012809928 hasAuthorship W2012809928A5088697304 @default.
- W2012809928 hasConcept C126322002 @default.
- W2012809928 hasConcept C142724271 @default.
- W2012809928 hasConcept C159654299 @default.
- W2012809928 hasConcept C163864487 @default.
- W2012809928 hasConcept C170493617 @default.
- W2012809928 hasConcept C203014093 @default.
- W2012809928 hasConcept C204232928 @default.
- W2012809928 hasConcept C2776362946 @default.
- W2012809928 hasConcept C2777546739 @default.
- W2012809928 hasConcept C2779409057 @default.
- W2012809928 hasConcept C2779438470 @default.
- W2012809928 hasConcept C542903549 @default.
- W2012809928 hasConcept C71924100 @default.
- W2012809928 hasConcept C74864618 @default.
- W2012809928 hasConcept C86803240 @default.
- W2012809928 hasConceptScore W2012809928C126322002 @default.
- W2012809928 hasConceptScore W2012809928C142724271 @default.
- W2012809928 hasConceptScore W2012809928C159654299 @default.
- W2012809928 hasConceptScore W2012809928C163864487 @default.
- W2012809928 hasConceptScore W2012809928C170493617 @default.
- W2012809928 hasConceptScore W2012809928C203014093 @default.
- W2012809928 hasConceptScore W2012809928C204232928 @default.
- W2012809928 hasConceptScore W2012809928C2776362946 @default.
- W2012809928 hasConceptScore W2012809928C2777546739 @default.
- W2012809928 hasConceptScore W2012809928C2779409057 @default.
- W2012809928 hasConceptScore W2012809928C2779438470 @default.
- W2012809928 hasConceptScore W2012809928C542903549 @default.
- W2012809928 hasConceptScore W2012809928C71924100 @default.
- W2012809928 hasConceptScore W2012809928C74864618 @default.
- W2012809928 hasConceptScore W2012809928C86803240 @default.
- W2012809928 hasIssue "2" @default.
- W2012809928 hasLocation W20128099281 @default.
- W2012809928 hasLocation W20128099282 @default.
- W2012809928 hasOpenAccess W2012809928 @default.