FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012810764> ?p ?o ?g. }

• W2012810764 endingPage "444" @default.
• W2012810764 startingPage "439" @default.
• W2012810764 abstract "PRAME (Preferentially expressed antigen of melanoma), highly expressed in various solid tumor cells and normal testis, was first isolated as a human melanoma antigen recognized by cytotoxic T cells (CTL). This gene was also expressed in some of the hematological malignancies, including acute myelogenous leukemia (AML) and multiple myeloma. We and others have extensively evaluated the PRAME expression in various hematological malignancies and demonstrated high expression of the PRAME gene in subsets of AML, chronic myelogenous leukemia, acute lymphocytic leukemia, lymphoma and multiple myeloma. In addition, we have demonstrated that PRAME was a useful marker for detection of minimal residual disease (MRD) in patients with leukemia, particularly those leukemias in which tumor specific markers are currently unavailable. Since PRAME was first identified as a tumor antigen recognized by T cells, the possibility that PRAME is a leukemia antigen recognized by T cells was evaluated, and it was found that PRAME-positive leukemia cell lines and fresh leukemia cells were susceptible to lysis by the PRAME-specific CTL. Five CTL epitopes associated with either HLA-A*0201 or HLA-A*2402 have recently been identified. It is, therefore, an attractive strategy to apply PRAME specific immunotherapy on patients with PRAME positive leukemia in MRD condition." @default.
• W2012810764 created "2016-06-24" @default.
• W2012810764 creator A5003368425 @default.
• W2012810764 creator A5021956519 @default.
• W2012810764 creator A5055290282 @default.
• W2012810764 creator A5089176517 @default.
• W2012810764 date "2003-01-01" @default.
• W2012810764 modified "2023-10-18" @default.
• W2012810764 title "Preferentially Expressed Antigen of Melanoma (PRAME) in the Development of Diagnostic and Therapeutic Methods for Hematological Malignancies" @default.
• W2012810764 cites W10348948 @default.
• W2012810764 cites W1482758361 @default.
• W2012810764 cites W1497974883 @default.
• W2012810764 cites W1558238582 @default.
• W2012810764 cites W177504901 @default.
• W2012810764 cites W1979574709 @default.
• W2012810764 cites W1983806918 @default.
• W2012810764 cites W1987698068 @default.
• W2012810764 cites W1993191461 @default.
• W2012810764 cites W1995541635 @default.
• W2012810764 cites W2030275902 @default.
• W2012810764 cites W2034110552 @default.
• W2012810764 cites W204705285 @default.
• W2012810764 cites W2049757773 @default.
• W2012810764 cites W2058490696 @default.
• W2012810764 cites W2066311819 @default.
• W2012810764 cites W2066964346 @default.
• W2012810764 cites W2073241357 @default.
• W2012810764 cites W2073462203 @default.
• W2012810764 cites W2075531452 @default.
• W2012810764 cites W2081386923 @default.
• W2012810764 cites W2117216774 @default.
• W2012810764 cites W2132925083 @default.
• W2012810764 cites W2159325547 @default.
• W2012810764 cites W2270388660 @default.
• W2012810764 cites W2321645223 @default.
• W2012810764 cites W2329925739 @default.
• W2012810764 cites W4312790597 @default.
• W2012810764 cites W4385970358 @default.
• W2012810764 cites W53690666 @default.
• W2012810764 cites W998391454 @default.
• W2012810764 doi "https://doi.org/10.1080/1042819021000035725" @default.
• W2012810764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12688312" @default.
• W2012810764 hasPublicationYear "2003" @default.
• W2012810764 type Work @default.
• W2012810764 sameAs 2012810764 @default.
• W2012810764 citedByCount "41" @default.
• W2012810764 countsByYear W20128107642013 @default.
• W2012810764 countsByYear W20128107642015 @default.
• W2012810764 countsByYear W20128107642019 @default.
• W2012810764 countsByYear W20128107642020 @default.
• W2012810764 countsByYear W20128107642021 @default.
• W2012810764 countsByYear W20128107642022 @default.
• W2012810764 countsByYear W20128107642023 @default.
• W2012810764 crossrefType "journal-article" @default.
• W2012810764 hasAuthorship W2012810764A5003368425 @default.
• W2012810764 hasAuthorship W2012810764A5021956519 @default.
• W2012810764 hasAuthorship W2012810764A5055290282 @default.
• W2012810764 hasAuthorship W2012810764A5089176517 @default.
• W2012810764 hasConcept C147483822 @default.
• W2012810764 hasConcept C147969180 @default.
• W2012810764 hasConcept C167672396 @default.
• W2012810764 hasConcept C203014093 @default.
• W2012810764 hasConcept C2776364478 @default.
• W2012810764 hasConcept C2777658100 @default.
• W2012810764 hasConcept C2777701055 @default.
• W2012810764 hasConcept C2778461978 @default.
• W2012810764 hasConcept C2779823535 @default.
• W2012810764 hasConcept C502942594 @default.
• W2012810764 hasConcept C71924100 @default.
• W2012810764 hasConcept C8891405 @default.
• W2012810764 hasConceptScore W2012810764C147483822 @default.
• W2012810764 hasConceptScore W2012810764C147969180 @default.
• W2012810764 hasConceptScore W2012810764C167672396 @default.
• W2012810764 hasConceptScore W2012810764C203014093 @default.
• W2012810764 hasConceptScore W2012810764C2776364478 @default.
• W2012810764 hasConceptScore W2012810764C2777658100 @default.
• W2012810764 hasConceptScore W2012810764C2777701055 @default.
• W2012810764 hasConceptScore W2012810764C2778461978 @default.
• W2012810764 hasConceptScore W2012810764C2779823535 @default.
• W2012810764 hasConceptScore W2012810764C502942594 @default.
• W2012810764 hasConceptScore W2012810764C71924100 @default.
• W2012810764 hasConceptScore W2012810764C8891405 @default.
• W2012810764 hasIssue "3" @default.
• W2012810764 hasLocation W20128107641 @default.
• W2012810764 hasLocation W20128107642 @default.
• W2012810764 hasOpenAccess W2012810764 @default.
• W2012810764 hasPrimaryLocation W20128107641 @default.
• W2012810764 hasRelatedWork W1549922507 @default.
• W2012810764 hasRelatedWork W1584466340 @default.
• W2012810764 hasRelatedWork W1605884721 @default.
• W2012810764 hasRelatedWork W1864390991 @default.
• W2012810764 hasRelatedWork W1985728487 @default.
• W2012810764 hasRelatedWork W202444208 @default.
• W2012810764 hasRelatedWork W2027917976 @default.
• W2012810764 hasRelatedWork W2032919665 @default.
• W2012810764 hasRelatedWork W2102262438 @default.
• W2012810764 hasRelatedWork W4239554058 @default.
• W2012810764 hasVolume "44" @default.

• next