Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012872746> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2012872746 endingPage "100" @default.
- W2012872746 startingPage "96" @default.
- W2012872746 abstract "To determine predictors of histological response to proton pump inhibitor (PPI) therapy among children with significant esophageal eosinophilia (SEE), defined as >or=15 eosinophils per high powered field (eos/hpf) on esophageal mucosal biopsy (EMB).Response to PPI therapy among children with SEE treated with PPI who underwent repeat EMB was studied retrospectively. Response was defined as <5 eos/hpf on repeat EMB. Characteristics of responders and nonresponders were analyzed.Of 326 patients (ages 1 through 18 years) diagnosed with SEE over a 7-year period, 43 (mean age, 8.5 years; 67% males) met inclusion criteria. After PPI therapy, 17 patients (40%) were responders. There were no significant differences in demographics, presenting symptoms, endoscopic, or histological findings between responders and nonresponders. Among patients with 15 to 20 eos/hpf on EMB, 50% were responders; among patients with >20 eos/hpf on EMB, 29% were responders. Seven of 17 (41%) patients with abnormal pH monitoring and 5 of 11 (45%) patients with normal monitoring were responders.Forty percent of patients with SEE demonstrated histological response to PPI therapy. None of the clinical characteristics evaluated predicted response, and response was not dependent on results of pH study. The role of PPI therapy in treating SEE warrants further prospective investigation." @default.
- W2012872746 created "2016-06-24" @default.
- W2012872746 creator A5008971974 @default.
- W2012872746 creator A5013346261 @default.
- W2012872746 creator A5026373653 @default.
- W2012872746 creator A5050101777 @default.
- W2012872746 creator A5060347270 @default.
- W2012872746 date "2009-01-01" @default.
- W2012872746 modified "2023-10-18" @default.
- W2012872746 title "Predictors of Response to Proton Pump Inhibitor Therapy among Children with Significant Esophageal Eosinophilia" @default.
- W2012872746 cites W1967595860 @default.
- W2012872746 cites W1974997545 @default.
- W2012872746 cites W1985180598 @default.
- W2012872746 cites W2019910323 @default.
- W2012872746 cites W2031413046 @default.
- W2012872746 cites W2032419156 @default.
- W2012872746 cites W2033306128 @default.
- W2012872746 cites W2033559734 @default.
- W2012872746 cites W2033805821 @default.
- W2012872746 cites W2034453465 @default.
- W2012872746 cites W2045156833 @default.
- W2012872746 cites W2049130296 @default.
- W2012872746 cites W2050496260 @default.
- W2012872746 cites W2072066727 @default.
- W2012872746 cites W2077290680 @default.
- W2012872746 cites W2083670549 @default.
- W2012872746 cites W2115407619 @default.
- W2012872746 cites W2129769279 @default.
- W2012872746 cites W2134207741 @default.
- W2012872746 cites W2142065538 @default.
- W2012872746 cites W2153162249 @default.
- W2012872746 cites W2158520583 @default.
- W2012872746 cites W2323763104 @default.
- W2012872746 cites W2325404226 @default.
- W2012872746 doi "https://doi.org/10.1016/j.jpeds.2008.07.042" @default.
- W2012872746 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18783791" @default.
- W2012872746 hasPublicationYear "2009" @default.
- W2012872746 type Work @default.
- W2012872746 sameAs 2012872746 @default.
- W2012872746 citedByCount "135" @default.
- W2012872746 countsByYear W20128727462012 @default.
- W2012872746 countsByYear W20128727462013 @default.
- W2012872746 countsByYear W20128727462014 @default.
- W2012872746 countsByYear W20128727462015 @default.
- W2012872746 countsByYear W20128727462016 @default.
- W2012872746 countsByYear W20128727462017 @default.
- W2012872746 countsByYear W20128727462018 @default.
- W2012872746 countsByYear W20128727462019 @default.
- W2012872746 countsByYear W20128727462020 @default.
- W2012872746 countsByYear W20128727462021 @default.
- W2012872746 countsByYear W20128727462022 @default.
- W2012872746 countsByYear W20128727462023 @default.
- W2012872746 crossrefType "journal-article" @default.
- W2012872746 hasAuthorship W2012872746A5008971974 @default.
- W2012872746 hasAuthorship W2012872746A5013346261 @default.
- W2012872746 hasAuthorship W2012872746A5026373653 @default.
- W2012872746 hasAuthorship W2012872746A5050101777 @default.
- W2012872746 hasAuthorship W2012872746A5060347270 @default.
- W2012872746 hasConcept C126322002 @default.
- W2012872746 hasConcept C144024400 @default.
- W2012872746 hasConcept C149923435 @default.
- W2012872746 hasConcept C188816634 @default.
- W2012872746 hasConcept C2775934546 @default.
- W2012872746 hasConcept C2777129736 @default.
- W2012872746 hasConcept C2780084366 @default.
- W2012872746 hasConcept C2781025758 @default.
- W2012872746 hasConcept C71924100 @default.
- W2012872746 hasConcept C90924648 @default.
- W2012872746 hasConceptScore W2012872746C126322002 @default.
- W2012872746 hasConceptScore W2012872746C144024400 @default.
- W2012872746 hasConceptScore W2012872746C149923435 @default.
- W2012872746 hasConceptScore W2012872746C188816634 @default.
- W2012872746 hasConceptScore W2012872746C2775934546 @default.
- W2012872746 hasConceptScore W2012872746C2777129736 @default.
- W2012872746 hasConceptScore W2012872746C2780084366 @default.
- W2012872746 hasConceptScore W2012872746C2781025758 @default.
- W2012872746 hasConceptScore W2012872746C71924100 @default.
- W2012872746 hasConceptScore W2012872746C90924648 @default.
- W2012872746 hasIssue "1" @default.
- W2012872746 hasLocation W20128727461 @default.
- W2012872746 hasLocation W20128727462 @default.
- W2012872746 hasOpenAccess W2012872746 @default.
- W2012872746 hasPrimaryLocation W20128727461 @default.
- W2012872746 hasRelatedWork W1775904578 @default.
- W2012872746 hasRelatedWork W2060297132 @default.
- W2012872746 hasRelatedWork W2123896274 @default.
- W2012872746 hasRelatedWork W2191917883 @default.
- W2012872746 hasRelatedWork W2234971496 @default.
- W2012872746 hasRelatedWork W2341239715 @default.
- W2012872746 hasRelatedWork W2892375549 @default.
- W2012872746 hasRelatedWork W2922809015 @default.
- W2012872746 hasRelatedWork W4236445795 @default.
- W2012872746 hasRelatedWork W4311068385 @default.
- W2012872746 hasVolume "154" @default.
- W2012872746 isParatext "false" @default.
- W2012872746 isRetracted "false" @default.
- W2012872746 magId "2012872746" @default.
- W2012872746 workType "article" @default.