Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012884543> ?p ?o ?g. }
- W2012884543 endingPage "1053" @default.
- W2012884543 startingPage "1045" @default.
- W2012884543 abstract "Xylella fastidiosa regulates traits important to both virulence of grape as well as colonization of sharpshooter vectors via its production of a fatty acid signal molecule known as DSF whose production is dependent on rpfF. Although X. fastidiosa rpfF mutants exhibit increased virulence to plants, they are unable to be spread from plant to plant by insect vectors. To gain more insight into the traits that contribute to these processes, a whole-genome Agilent DNA microarray for this species was developed and used to determine the RpfF-dependent regulon by transcriptional profiling. In total, 446 protein coding genes whose expression was significantly different between the wild type and an rpfF mutant (false discovery rate < 0.05) were identified when cells were grown in PW liquid medium. Among them, 165 genes were downregulated in the rpfF mutant compared with the wild-type strain whereas 281 genes were over-expressed. RpfF function was required for regulation of 11 regulatory and σ factors, including rpfE, yybA, PD1177, glnB, rpfG, PD0954, PD0199, PD2050, colR, rpoH, and rpoD. In general, RpfF is required for regulation of genes involved in attachment and biofilm formation, enhancing expression of hemagglutinin genes hxfA and hxfB, and suppressing most type IV pili and gum genes. A large number of other RpfF-dependent genes that might contribute to virulence or insect colonization were also identified such as those encoding hemolysin and colicin V, as well as genes with unknown functions." @default.
- W2012884543 created "2016-06-24" @default.
- W2012884543 creator A5026548190 @default.
- W2012884543 creator A5070818899 @default.
- W2012884543 creator A5082220656 @default.
- W2012884543 date "2012-11-01" @default.
- W2012884543 modified "2023-10-17" @default.
- W2012884543 title "RpfF-Dependent Regulon of <i>Xylella fastidiosa</i>" @default.
- W2012884543 cites W1509784654 @default.
- W2012884543 cites W1821747600 @default.
- W2012884543 cites W1964778865 @default.
- W2012884543 cites W1970486529 @default.
- W2012884543 cites W1979211129 @default.
- W2012884543 cites W1984935516 @default.
- W2012884543 cites W1985587585 @default.
- W2012884543 cites W1985789199 @default.
- W2012884543 cites W1988558672 @default.
- W2012884543 cites W1991974553 @default.
- W2012884543 cites W1992194734 @default.
- W2012884543 cites W1992780831 @default.
- W2012884543 cites W1994639724 @default.
- W2012884543 cites W2022876411 @default.
- W2012884543 cites W2022983919 @default.
- W2012884543 cites W2025139458 @default.
- W2012884543 cites W2030589189 @default.
- W2012884543 cites W2042107960 @default.
- W2012884543 cites W2042354470 @default.
- W2012884543 cites W2050628480 @default.
- W2012884543 cites W2052857973 @default.
- W2012884543 cites W2056932987 @default.
- W2012884543 cites W2057797117 @default.
- W2012884543 cites W2060415998 @default.
- W2012884543 cites W2081098333 @default.
- W2012884543 cites W2081615800 @default.
- W2012884543 cites W2100668965 @default.
- W2012884543 cites W2100702430 @default.
- W2012884543 cites W2105173502 @default.
- W2012884543 cites W2105876183 @default.
- W2012884543 cites W2106254491 @default.
- W2012884543 cites W2107277218 @default.
- W2012884543 cites W2107304641 @default.
- W2012884543 cites W2112830991 @default.
- W2012884543 cites W2115302225 @default.
- W2012884543 cites W2125480801 @default.
- W2012884543 cites W2131622674 @default.
- W2012884543 cites W2132759034 @default.
- W2012884543 cites W2136496240 @default.
- W2012884543 cites W2144003845 @default.
- W2012884543 cites W2145441064 @default.
- W2012884543 cites W2145922338 @default.
- W2012884543 cites W2146890648 @default.
- W2012884543 cites W2147881376 @default.
- W2012884543 cites W2153219269 @default.
- W2012884543 cites W2155399472 @default.
- W2012884543 cites W2162257514 @default.
- W2012884543 cites W2162519470 @default.
- W2012884543 cites W2162907250 @default.
- W2012884543 cites W2163101456 @default.
- W2012884543 cites W2166588567 @default.
- W2012884543 cites W2167174541 @default.
- W2012884543 cites W2167454930 @default.
- W2012884543 cites W2172255755 @default.
- W2012884543 cites W2176736579 @default.
- W2012884543 cites W2178726575 @default.
- W2012884543 cites W4241618946 @default.
- W2012884543 doi "https://doi.org/10.1094/phyto-07-12-0146-r" @default.
- W2012884543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22877314" @default.
- W2012884543 hasPublicationYear "2012" @default.
- W2012884543 type Work @default.
- W2012884543 sameAs 2012884543 @default.
- W2012884543 citedByCount "37" @default.
- W2012884543 countsByYear W20128845432013 @default.
- W2012884543 countsByYear W20128845432014 @default.
- W2012884543 countsByYear W20128845432015 @default.
- W2012884543 countsByYear W20128845432016 @default.
- W2012884543 countsByYear W20128845432017 @default.
- W2012884543 countsByYear W20128845432018 @default.
- W2012884543 countsByYear W20128845432019 @default.
- W2012884543 countsByYear W20128845432020 @default.
- W2012884543 countsByYear W20128845432021 @default.
- W2012884543 countsByYear W20128845432023 @default.
- W2012884543 crossrefType "journal-article" @default.
- W2012884543 hasAuthorship W2012884543A5026548190 @default.
- W2012884543 hasAuthorship W2012884543A5070818899 @default.
- W2012884543 hasAuthorship W2012884543A5082220656 @default.
- W2012884543 hasBestOaLocation W20128845431 @default.
- W2012884543 hasConcept C104317684 @default.
- W2012884543 hasConcept C118687296 @default.
- W2012884543 hasConcept C143065580 @default.
- W2012884543 hasConcept C2778410202 @default.
- W2012884543 hasConcept C523546767 @default.
- W2012884543 hasConcept C54355233 @default.
- W2012884543 hasConcept C60987743 @default.
- W2012884543 hasConcept C62361671 @default.
- W2012884543 hasConcept C86803240 @default.
- W2012884543 hasConcept C89423630 @default.
- W2012884543 hasConceptScore W2012884543C104317684 @default.
- W2012884543 hasConceptScore W2012884543C118687296 @default.