Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012887958> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2012887958 endingPage "190" @default.
- W2012887958 startingPage "187" @default.
- W2012887958 abstract "Subacute sclerosing panencephalitis (SSPE) is a progressive inflammatory and degenerative disorder of the central nervous system. Several factors influence the risk of chronic brain infection with the mutant measles virus. However, to date, no pathogenic mechanism that may predispose to SSPE has been determined. Studies have indicated that specific polymorphisms in certain host genes are probably involved in impairing the ability of host immune cells to eradicate the measles virus in SSPE patients. Programmed cell death protein 1 (PD-1), a member of the CD28 family, is a negative regulator of the immune system. The purpose of our study was to investigate whether PD-1 gene polymorphisms affect susceptibility to the development of SSPE in Turkish children. In total, 109 subjects (54 SSPE patients and 55 healthy controls) were genotyped for the PD-1.9 C/T (rs2227982) single-nucleotide polymorphism (SNP). The distributions of T alleles in the PD-1.9 polymorphism in SSPE patients and healthy controls were 2.8 and 10.9%, respectively. There was a statistically significant difference between the groups; the 95% confidence interval (CI) was 0.06 to 0.85 and the odds ratio (OR) was 0.23 (χ(2) test). Thus, we identified an association between SSPE and the PD-1 rs2227982 gene polymorphism; the frequency of T alleles was higher in controls than in SSPE patients." @default.
- W2012887958 created "2016-06-24" @default.
- W2012887958 creator A5025730588 @default.
- W2012887958 creator A5043758310 @default.
- W2012887958 creator A5046507275 @default.
- W2012887958 creator A5048337290 @default.
- W2012887958 creator A5058370453 @default.
- W2012887958 creator A5087616475 @default.
- W2012887958 date "2013-03-16" @default.
- W2012887958 modified "2023-09-29" @default.
- W2012887958 title "PD-1 Gene Polymorphism in Children with Subacute Sclerosing Panencephalitis" @default.
- W2012887958 doi "https://doi.org/10.1055/s-0033-1338134" @default.
- W2012887958 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23504559" @default.
- W2012887958 hasPublicationYear "2013" @default.
- W2012887958 type Work @default.
- W2012887958 sameAs 2012887958 @default.
- W2012887958 citedByCount "12" @default.
- W2012887958 countsByYear W20128879582013 @default.
- W2012887958 countsByYear W20128879582014 @default.
- W2012887958 countsByYear W20128879582016 @default.
- W2012887958 countsByYear W20128879582018 @default.
- W2012887958 countsByYear W20128879582021 @default.
- W2012887958 countsByYear W20128879582022 @default.
- W2012887958 countsByYear W20128879582023 @default.
- W2012887958 crossrefType "journal-article" @default.
- W2012887958 hasAuthorship W2012887958A5025730588 @default.
- W2012887958 hasAuthorship W2012887958A5043758310 @default.
- W2012887958 hasAuthorship W2012887958A5046507275 @default.
- W2012887958 hasAuthorship W2012887958A5048337290 @default.
- W2012887958 hasAuthorship W2012887958A5058370453 @default.
- W2012887958 hasAuthorship W2012887958A5087616475 @default.
- W2012887958 hasConcept C104317684 @default.
- W2012887958 hasConcept C126322002 @default.
- W2012887958 hasConcept C135763542 @default.
- W2012887958 hasConcept C153209595 @default.
- W2012887958 hasConcept C156957248 @default.
- W2012887958 hasConcept C180754005 @default.
- W2012887958 hasConcept C203014093 @default.
- W2012887958 hasConcept C22070199 @default.
- W2012887958 hasConcept C2776264772 @default.
- W2012887958 hasConcept C2776438120 @default.
- W2012887958 hasConcept C2778199166 @default.
- W2012887958 hasConcept C54355233 @default.
- W2012887958 hasConcept C71924100 @default.
- W2012887958 hasConcept C86803240 @default.
- W2012887958 hasConcept C8891405 @default.
- W2012887958 hasConceptScore W2012887958C104317684 @default.
- W2012887958 hasConceptScore W2012887958C126322002 @default.
- W2012887958 hasConceptScore W2012887958C135763542 @default.
- W2012887958 hasConceptScore W2012887958C153209595 @default.
- W2012887958 hasConceptScore W2012887958C156957248 @default.
- W2012887958 hasConceptScore W2012887958C180754005 @default.
- W2012887958 hasConceptScore W2012887958C203014093 @default.
- W2012887958 hasConceptScore W2012887958C22070199 @default.
- W2012887958 hasConceptScore W2012887958C2776264772 @default.
- W2012887958 hasConceptScore W2012887958C2776438120 @default.
- W2012887958 hasConceptScore W2012887958C2778199166 @default.
- W2012887958 hasConceptScore W2012887958C54355233 @default.
- W2012887958 hasConceptScore W2012887958C71924100 @default.
- W2012887958 hasConceptScore W2012887958C86803240 @default.
- W2012887958 hasConceptScore W2012887958C8891405 @default.
- W2012887958 hasIssue "04" @default.
- W2012887958 hasLocation W20128879581 @default.
- W2012887958 hasLocation W20128879582 @default.
- W2012887958 hasOpenAccess W2012887958 @default.
- W2012887958 hasPrimaryLocation W20128879581 @default.
- W2012887958 hasRelatedWork W1604695931 @default.
- W2012887958 hasRelatedWork W1766341308 @default.
- W2012887958 hasRelatedWork W1820826924 @default.
- W2012887958 hasRelatedWork W1996340012 @default.
- W2012887958 hasRelatedWork W1997059393 @default.
- W2012887958 hasRelatedWork W2012147008 @default.
- W2012887958 hasRelatedWork W2016515168 @default.
- W2012887958 hasRelatedWork W2036454960 @default.
- W2012887958 hasRelatedWork W2099939036 @default.
- W2012887958 hasRelatedWork W2144428825 @default.
- W2012887958 hasVolume "44" @default.
- W2012887958 isParatext "false" @default.
- W2012887958 isRetracted "false" @default.
- W2012887958 magId "2012887958" @default.
- W2012887958 workType "article" @default.