Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012891036> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2012891036 endingPage "1191" @default.
- W2012891036 startingPage "1185" @default.
- W2012891036 abstract "Radiosyntheses of two N3-substituted thymidine analogues, N3-[(4[18F]fluoromethyl-phenyl)butyl]thymidine ([18F]-FMPBT) and N3-[(4[18F]fluoromethyl-phenyl)pentyl]thymidine ([18F]-FMPPT), are reported. The precursor compounds 9 and 10 were synthesized in six steps and the standard compounds 13 and 14 were synthesized from these precursors. For radiosynthesis, compounds 9 and 10 were fluorinated with n-Bu4N[18F] to produce [18F]-11 and [18F]-12, which by acid hydrolysis yielded [18F]-13 and [18F]-14, respectively. The crude products were purified by high-performance liquid chromatography to obtain [18F]-FMPBT and [18F]-FMPPT. The average decay-corrected radiochemical yield for [18F]-13 was 15% in five runs, and that for [18F]-14 was 10% in four runs. The radiochemical purity was >99% and the specific activity was >74 GBq/µmol at the end of synthesis. The synthesis time was 80–90 min from the end of bombardment. Copyright © 2007 John Wiley & Sons, Ltd." @default.
- W2012891036 created "2016-06-24" @default.
- W2012891036 creator A5037658628 @default.
- W2012891036 creator A5064151398 @default.
- W2012891036 creator A5065040550 @default.
- W2012891036 date "2007-01-01" @default.
- W2012891036 modified "2023-09-24" @default.
- W2012891036 title "N3-Substituted thymidine analogues III: radiosynthesis of N3-[(4-[18F]fluoromethyl-phenyl)butyl]thymidine ([18F]-FMPBT) and N3-[(4-[18F]fluoromethyl-phenyl)pentyl] thymidine ([18F]-FMPPT) for PET" @default.
- W2012891036 cites W12167749 @default.
- W2012891036 cites W1514058220 @default.
- W2012891036 cites W1965410568 @default.
- W2012891036 cites W1969012553 @default.
- W2012891036 cites W1979324961 @default.
- W2012891036 cites W1980718355 @default.
- W2012891036 cites W1988518808 @default.
- W2012891036 cites W2003947111 @default.
- W2012891036 cites W2006646656 @default.
- W2012891036 cites W2011611432 @default.
- W2012891036 cites W2021230697 @default.
- W2012891036 cites W2024928163 @default.
- W2012891036 cites W2026688674 @default.
- W2012891036 cites W2030672408 @default.
- W2012891036 cites W2033676601 @default.
- W2012891036 cites W2038057738 @default.
- W2012891036 cites W2043550097 @default.
- W2012891036 cites W2051432540 @default.
- W2012891036 cites W2056909940 @default.
- W2012891036 cites W2058893139 @default.
- W2012891036 cites W2060462693 @default.
- W2012891036 cites W2073297613 @default.
- W2012891036 cites W2076544479 @default.
- W2012891036 cites W2086184737 @default.
- W2012891036 cites W2094811518 @default.
- W2012891036 cites W2115229958 @default.
- W2012891036 cites W2117508315 @default.
- W2012891036 cites W2154089985 @default.
- W2012891036 doi "https://doi.org/10.1002/jlcr.1425" @default.
- W2012891036 hasPublicationYear "2007" @default.
- W2012891036 type Work @default.
- W2012891036 sameAs 2012891036 @default.
- W2012891036 citedByCount "5" @default.
- W2012891036 countsByYear W20128910362013 @default.
- W2012891036 countsByYear W20128910362020 @default.
- W2012891036 crossrefType "journal-article" @default.
- W2012891036 hasAuthorship W2012891036A5037658628 @default.
- W2012891036 hasAuthorship W2012891036A5064151398 @default.
- W2012891036 hasAuthorship W2012891036A5065040550 @default.
- W2012891036 hasConcept C134121241 @default.
- W2012891036 hasConcept C150903083 @default.
- W2012891036 hasConcept C155647269 @default.
- W2012891036 hasConcept C177322064 @default.
- W2012891036 hasConcept C178790620 @default.
- W2012891036 hasConcept C185592680 @default.
- W2012891036 hasConcept C191897082 @default.
- W2012891036 hasConcept C192562407 @default.
- W2012891036 hasConcept C202751555 @default.
- W2012891036 hasConcept C207001950 @default.
- W2012891036 hasConcept C2776970183 @default.
- W2012891036 hasConcept C2777108182 @default.
- W2012891036 hasConcept C55493867 @default.
- W2012891036 hasConcept C71240020 @default.
- W2012891036 hasConcept C86803240 @default.
- W2012891036 hasConcept C94412978 @default.
- W2012891036 hasConceptScore W2012891036C134121241 @default.
- W2012891036 hasConceptScore W2012891036C150903083 @default.
- W2012891036 hasConceptScore W2012891036C155647269 @default.
- W2012891036 hasConceptScore W2012891036C177322064 @default.
- W2012891036 hasConceptScore W2012891036C178790620 @default.
- W2012891036 hasConceptScore W2012891036C185592680 @default.
- W2012891036 hasConceptScore W2012891036C191897082 @default.
- W2012891036 hasConceptScore W2012891036C192562407 @default.
- W2012891036 hasConceptScore W2012891036C202751555 @default.
- W2012891036 hasConceptScore W2012891036C207001950 @default.
- W2012891036 hasConceptScore W2012891036C2776970183 @default.
- W2012891036 hasConceptScore W2012891036C2777108182 @default.
- W2012891036 hasConceptScore W2012891036C55493867 @default.
- W2012891036 hasConceptScore W2012891036C71240020 @default.
- W2012891036 hasConceptScore W2012891036C86803240 @default.
- W2012891036 hasConceptScore W2012891036C94412978 @default.
- W2012891036 hasIssue "13" @default.
- W2012891036 hasLocation W20128910361 @default.
- W2012891036 hasOpenAccess W2012891036 @default.
- W2012891036 hasPrimaryLocation W20128910361 @default.
- W2012891036 hasRelatedWork W1492828145 @default.
- W2012891036 hasRelatedWork W2017640674 @default.
- W2012891036 hasRelatedWork W2086184737 @default.
- W2012891036 hasRelatedWork W2095581038 @default.
- W2012891036 hasRelatedWork W2097014657 @default.
- W2012891036 hasRelatedWork W2325193303 @default.
- W2012891036 hasRelatedWork W2776585168 @default.
- W2012891036 hasRelatedWork W2792585236 @default.
- W2012891036 hasRelatedWork W2950717927 @default.
- W2012891036 hasRelatedWork W4224311418 @default.
- W2012891036 hasVolume "50" @default.
- W2012891036 isParatext "false" @default.
- W2012891036 isRetracted "false" @default.
- W2012891036 magId "2012891036" @default.
- W2012891036 workType "article" @default.