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• W2012904436 abstract "The goal of this study was to measure the interindividual reproducibility of glutamate quantification in 1.5-T 1H MRS of human brains. To determine the effective echo time (TE) for glutamate quantification, spectra from a phantom and 12 participants were obtained with TE = 30, 35, 40, and 144 ms (repetition time (TR) = 2000 ms and volume of interest = 4 cm3). The average Cramér–Rao lower bounds for glutamate quantification using LCModel was lowest in two experiments when TE = 40 ms. Twenty-one subjects participated in experiments that measured interindividual reproducibility of glutamate quantification. Spectra were acquired with TR = 6000 ms and TE = 40 ms. Results showed that the coefficients of variance were 11.0 and 13.1% in the anterior cingulate cortex and insula, respectively. This suggests that glutamate can be reproducibly measured from 1.5-T 1H MRS with long TR, effective TE, and the LCModel. Magn Reson Med 53:708–712, 2005. © 2005 Wiley-Liss, Inc." @default.
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• W2012904436 date "2005-01-01" @default.
• W2012904436 modified "2023-10-16" @default.
• W2012904436 title "Interindividual reproducibility of glutamate quantification using 1.5-T proton magnetic resonance spectroscopy" @default.
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• W2012904436 doi "https://doi.org/10.1002/mrm.20387" @default.
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