FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012946918> ?p ?o ?g. }

• W2012946918 endingPage "206" @default.
• W2012946918 startingPage "193" @default.
• W2012946918 abstract "Administration of iodinated contrast media (CM) for radiographic purposes is a preoccupying cause of acute renal failure. This review of the literature deals with what is known about physiopathology, clinical course, risk factors and prevention. Factors involved in the pathophysiology of CM-induced acute renal failure are vasoconstriction, direct tubular cell injury and tubular obstruction by casts. In the case of pre-existing renal hypoperfusion, CM may disturb the complex interaction between factors which modulate renal haemodynamics by increasing vasoconstrictor factors, notably endothelin peptides. The renal medulla, a zone characterized by a high metabolic activity and a low oxygen tension, may be a specific target for CM-induced effects. CM-induced nephropathy (CMN) is essentially observed in patients with one or more associated risk factors (chronic renal failure, dehydration, diabetes mellitus with impaired renal function, multiple myeloma, large CM volume, intra-arterial rather than intravenous route, etc). There is much debate as to whether newer low osmolar CM (LOCM) are better tolerated than conventional high osmolar CM (HOCM). Most of the animal studies clearly demonstrate the advantages of LOCM over HOCM. Clinical literature is far more confusing, although some recent studies and one meta-analysis demonstrate that LOCM are better tolerated in patients with impaired renal function. The low number of comparative clinical trials carried out in high risk patients, wide variability in CMN definitions, limited number of patients enrolled and inadequacy of various selected endpoints may explain difficulties experienced in demonstrating this advantage. Furthermore, while hydration is correctly maintained during clinical trials, this is not always true in clinical practice. Such a discrepancy could lead to underestimation of the potential advantage of LOCM over HOCM. Effective prevention should associate the correct hydration of patients, identification and, when possible, optimal correction of risk factors, avoidance of repeated CM injections within a short period of time and temporary disruption of treatment with other nephrotoxic drugs (non steroidal antiinflammatory drugs, aminoglycosides, etc)." @default.
• W2012946918 created "2016-06-24" @default.
• W2012946918 creator A5042176427 @default.
• W2012946918 creator A5056239597 @default.
• W2012946918 creator A5058423035 @default.
• W2012946918 date "1994-05-06" @default.
• W2012946918 modified "2023-10-16" @default.
• W2012946918 title "Iodinated contrast media-induced nephropathy: pathophysiology, clinical aspects and prevention" @default.
• W2012946918 cites W1550111394 @default.
• W2012946918 cites W1967760548 @default.
• W2012946918 cites W1973023384 @default.
• W2012946918 cites W1976435650 @default.
• W2012946918 cites W1976474677 @default.
• W2012946918 cites W1979043418 @default.
• W2012946918 cites W1979595865 @default.
• W2012946918 cites W1980489046 @default.
• W2012946918 cites W1986262243 @default.
• W2012946918 cites W1988044417 @default.
• W2012946918 cites W1988404760 @default.
• W2012946918 cites W1989769216 @default.
• W2012946918 cites W1993706286 @default.
• W2012946918 cites W1995299854 @default.
• W2012946918 cites W1996333849 @default.
• W2012946918 cites W1997772915 @default.
• W2012946918 cites W2000739059 @default.
• W2012946918 cites W2006822557 @default.
• W2012946918 cites W2008114066 @default.
• W2012946918 cites W2016702021 @default.
• W2012946918 cites W2017118621 @default.
• W2012946918 cites W2018128965 @default.
• W2012946918 cites W2023444649 @default.
• W2012946918 cites W2024794265 @default.
• W2012946918 cites W2027695475 @default.
• W2012946918 cites W2029204995 @default.
• W2012946918 cites W2032097996 @default.
• W2012946918 cites W2032949562 @default.
• W2012946918 cites W2035961834 @default.
• W2012946918 cites W2041086283 @default.
• W2012946918 cites W2042106394 @default.
• W2012946918 cites W2043942075 @default.
• W2012946918 cites W2045334074 @default.
• W2012946918 cites W2045840628 @default.
• W2012946918 cites W2047107921 @default.
• W2012946918 cites W2047123619 @default.
• W2012946918 cites W2047474179 @default.
• W2012946918 cites W2055640006 @default.
• W2012946918 cites W2056231185 @default.
• W2012946918 cites W2057042537 @default.
• W2012946918 cites W2059649210 @default.
• W2012946918 cites W2066294224 @default.
• W2012946918 cites W2068384982 @default.
• W2012946918 cites W2071361185 @default.
• W2012946918 cites W2072571457 @default.
• W2012946918 cites W2073085411 @default.
• W2012946918 cites W2074202927 @default.
• W2012946918 cites W2079344598 @default.
• W2012946918 cites W2080965838 @default.
• W2012946918 cites W2082867695 @default.
• W2012946918 cites W2083796803 @default.
• W2012946918 cites W2088746152 @default.
• W2012946918 cites W2090718409 @default.
• W2012946918 cites W2091443934 @default.
• W2012946918 cites W2091631461 @default.
• W2012946918 cites W2091670507 @default.
• W2012946918 cites W2092019333 @default.
• W2012946918 cites W2122533932 @default.
• W2012946918 cites W2130446222 @default.
• W2012946918 cites W2133037098 @default.
• W2012946918 cites W2135288639 @default.
• W2012946918 cites W2140143996 @default.
• W2012946918 cites W2156998972 @default.
• W2012946918 cites W2167747277 @default.
• W2012946918 cites W2171998192 @default.
• W2012946918 cites W2185254863 @default.
• W2012946918 cites W2189378267 @default.
• W2012946918 cites W2316461329 @default.
• W2012946918 cites W2319889543 @default.
• W2012946918 cites W2399966274 @default.
• W2012946918 cites W4239172270 @default.
• W2012946918 cites W4248635938 @default.
• W2012946918 cites W4250948006 @default.
• W2012946918 cites W4317564087 @default.
• W2012946918 doi "https://doi.org/10.1111/j.1472-8206.1994.tb00799.x" @default.
• W2012946918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7927115" @default.
• W2012946918 hasPublicationYear "1994" @default.
• W2012946918 type Work @default.
• W2012946918 sameAs 2012946918 @default.
• W2012946918 citedByCount "43" @default.
• W2012946918 countsByYear W20129469182012 @default.
• W2012946918 countsByYear W20129469182013 @default.
• W2012946918 countsByYear W20129469182014 @default.
• W2012946918 countsByYear W20129469182015 @default.
• W2012946918 countsByYear W20129469182016 @default.
• W2012946918 countsByYear W20129469182018 @default.
• W2012946918 crossrefType "journal-article" @default.
• W2012946918 hasAuthorship W2012946918A5042176427 @default.
• W2012946918 hasAuthorship W2012946918A5056239597 @default.
• W2012946918 hasAuthorship W2012946918A5058423035 @default.

• next