FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012952384> ?p ?o ?g. }

• W2012952384 endingPage "74" @default.
• W2012952384 startingPage "66" @default.
• W2012952384 abstract "Evidence indicates that endogenous opioids play a role in body temperature (Tb) regulation in mammals but no data exist about the involvement of the specific opioid receptors, mu, kappa and delta, in the reduction of Tb induced by hypoxia. Thus, we investigated the participation of these opioid receptors in the anteroventral preoptic region (AVPO) in hypoxic decrease of Tb. To this end, Tb of unanesthetized Wistar rats was monitored by temperature data loggers before and after intra-AVPO microinjection of the selective kappa-opioid receptor antagonist nor-binaltorphimine dihydrochloride (nor-BNI; 0.1 and 1.0 microg/100 nL/animal), the selective mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 cyclic (CTAP; 0.1 and 1.0 microg/100 nL/animal), and the selective delta-opioid receptor antagonist Naltrindole (0.06 and 0.6 microg/100 nL/animal) or saline (vehicle, 100 nL/animal), during normoxia and hypoxia (7% inspired O2). Under normoxia, no effect of opioid antagonists on Tb was observed. Hypoxia induced Tb to reduce in vehicle group, a response that was inhibited by the microinjection intra-AVPO of nor-BNI. In contrast, CTAP and Naltrindole did not change Tb during hypoxia but caused a longer latency for the return of Tb to the normoxic values just after low O2 exposure. Our results indicate the kappa-opioid receptor in the AVPO is important for the reduction of Tb during hypoxia while the mu and delta receptors are involved in the increase of Tb during normoxia post-hypoxia." @default.
• W2012952384 created "2016-06-24" @default.
• W2012952384 creator A5000194947 @default.
• W2012952384 creator A5023509015 @default.
• W2012952384 creator A5029649532 @default.
• W2012952384 creator A5068876663 @default.
• W2012952384 date "2009-08-01" @default.
• W2012952384 modified "2023-10-16" @default.
• W2012952384 title "Role of preoptic opioid receptors in the body temperature reduction during hypoxia" @default.
• W2012952384 cites W1929626856 @default.
• W2012952384 cites W1933050657 @default.
• W2012952384 cites W1966182087 @default.
• W2012952384 cites W1967200412 @default.
• W2012952384 cites W1971040026 @default.
• W2012952384 cites W1971234533 @default.
• W2012952384 cites W1973816523 @default.
• W2012952384 cites W1987891804 @default.
• W2012952384 cites W1990726828 @default.
• W2012952384 cites W1990876574 @default.
• W2012952384 cites W1992916143 @default.
• W2012952384 cites W1993531577 @default.
• W2012952384 cites W1994510048 @default.
• W2012952384 cites W1997541372 @default.
• W2012952384 cites W2001266985 @default.
• W2012952384 cites W2005769782 @default.
• W2012952384 cites W2008509812 @default.
• W2012952384 cites W2008814999 @default.
• W2012952384 cites W2009545592 @default.
• W2012952384 cites W2011511958 @default.
• W2012952384 cites W2017503924 @default.
• W2012952384 cites W2017528401 @default.
• W2012952384 cites W2017860510 @default.
• W2012952384 cites W2019010747 @default.
• W2012952384 cites W2029914471 @default.
• W2012952384 cites W2032592237 @default.
• W2012952384 cites W2038623076 @default.
• W2012952384 cites W2043671285 @default.
• W2012952384 cites W2045316217 @default.
• W2012952384 cites W2049382766 @default.
• W2012952384 cites W2049973237 @default.
• W2012952384 cites W2055630157 @default.
• W2012952384 cites W2060198335 @default.
• W2012952384 cites W2062346120 @default.
• W2012952384 cites W2063137503 @default.
• W2012952384 cites W2070692593 @default.
• W2012952384 cites W2072484623 @default.
• W2012952384 cites W2078003926 @default.
• W2012952384 cites W2079167959 @default.
• W2012952384 cites W2084646626 @default.
• W2012952384 cites W2084821106 @default.
• W2012952384 cites W2085733618 @default.
• W2012952384 cites W2086855996 @default.
• W2012952384 cites W2094973127 @default.
• W2012952384 cites W2096659617 @default.
• W2012952384 cites W2110549109 @default.
• W2012952384 cites W2120506552 @default.
• W2012952384 cites W2122641630 @default.
• W2012952384 cites W2132164381 @default.
• W2012952384 cites W2143092775 @default.
• W2012952384 cites W2158329247 @default.
• W2012952384 cites W2158813176 @default.
• W2012952384 cites W2160328264 @default.
• W2012952384 cites W2165874451 @default.
• W2012952384 cites W2168603460 @default.
• W2012952384 cites W2172323892 @default.
• W2012952384 cites W2178852427 @default.
• W2012952384 cites W2340582635 @default.
• W2012952384 cites W2596009609 @default.
• W2012952384 cites W4300983000 @default.
• W2012952384 doi "https://doi.org/10.1016/j.brainres.2009.06.039" @default.
• W2012952384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19545549" @default.
• W2012952384 hasPublicationYear "2009" @default.
• W2012952384 type Work @default.
• W2012952384 sameAs 2012952384 @default.
• W2012952384 citedByCount "23" @default.
• W2012952384 countsByYear W20129523842012 @default.
• W2012952384 countsByYear W20129523842013 @default.
• W2012952384 countsByYear W20129523842014 @default.
• W2012952384 countsByYear W20129523842017 @default.
• W2012952384 countsByYear W20129523842018 @default.
• W2012952384 countsByYear W20129523842019 @default.
• W2012952384 countsByYear W20129523842020 @default.
• W2012952384 countsByYear W20129523842021 @default.
• W2012952384 crossrefType "journal-article" @default.
• W2012952384 hasAuthorship W2012952384A5000194947 @default.
• W2012952384 hasAuthorship W2012952384A5023509015 @default.
• W2012952384 hasAuthorship W2012952384A5029649532 @default.
• W2012952384 hasAuthorship W2012952384A5068876663 @default.
• W2012952384 hasBestOaLocation W20129523841 @default.
• W2012952384 hasConcept C126322002 @default.
• W2012952384 hasConcept C134018914 @default.
• W2012952384 hasConcept C141087196 @default.
• W2012952384 hasConcept C170493617 @default.
• W2012952384 hasConcept C178790620 @default.
• W2012952384 hasConcept C184389661 @default.
• W2012952384 hasConcept C185592680 @default.
• W2012952384 hasConcept C2776885963 @default.
• W2012952384 hasConcept C2777953665 @default.

• next