Matches in SemOpenAlex for { <https://semopenalex.org/work/W2012968596> ?p ?o ?g. }
- W2012968596 endingPage "1220" @default.
- W2012968596 startingPage "1209" @default.
- W2012968596 abstract "The guanidinium functional group is commonly used in nature to recognize and bind anions through ion pairing and hydrogen bonding. Specific hydrogen-bonding patterns can be found in crystal structures of simple guanidinium salts. Analysis of these simple salts reveals a variety of features which are found in natural systems. These features have been applied to a series of artificial phosphodiesterases for RNA. These receptors incorporate guanidinium groups positioned to mimic the hydrogen-bonding patterns found in simple guanidinium salts and natural enzymes. This paper outlines general guanidinium hydrogen-bonding patterns. Next, the complexation of phosphodiesters with a series of artificial receptors are analyzed in terms of counterions, solvent mixtures, and cavity flexibility. In addition, strategies to enhance catalysis through a pKa analysis of phosphoranes are addressed. Next, we describe how our findings were incorporated into second generation receptors/catalysts. Finally, our future work is discussed." @default.
- W2012968596 created "2016-06-24" @default.
- W2012968596 creator A5033744233 @default.
- W2012968596 creator A5066428999 @default.
- W2012968596 creator A5070599064 @default.
- W2012968596 date "1997-06-01" @default.
- W2012968596 modified "2023-10-16" @default.
- W2012968596 title "Using guanidinium groups for the recognition of RNA and as catalysts for the hydrolysis of RNA" @default.
- W2012968596 cites W1954690293 @default.
- W2012968596 cites W1957422323 @default.
- W2012968596 cites W1978997177 @default.
- W2012968596 cites W1985474448 @default.
- W2012968596 cites W1988795129 @default.
- W2012968596 cites W1989724985 @default.
- W2012968596 cites W1989855629 @default.
- W2012968596 cites W1992557049 @default.
- W2012968596 cites W1993984936 @default.
- W2012968596 cites W2002680288 @default.
- W2012968596 cites W2003351109 @default.
- W2012968596 cites W2006775197 @default.
- W2012968596 cites W2006913439 @default.
- W2012968596 cites W2010038629 @default.
- W2012968596 cites W2012675110 @default.
- W2012968596 cites W2012962727 @default.
- W2012968596 cites W2019105338 @default.
- W2012968596 cites W2027188081 @default.
- W2012968596 cites W2031155729 @default.
- W2012968596 cites W2031493515 @default.
- W2012968596 cites W2034736903 @default.
- W2012968596 cites W2035783320 @default.
- W2012968596 cites W2037849444 @default.
- W2012968596 cites W2048460207 @default.
- W2012968596 cites W2051188149 @default.
- W2012968596 cites W2052437655 @default.
- W2012968596 cites W2055378639 @default.
- W2012968596 cites W2057488512 @default.
- W2012968596 cites W2061485208 @default.
- W2012968596 cites W2065056612 @default.
- W2012968596 cites W2067887310 @default.
- W2012968596 cites W2068372163 @default.
- W2012968596 cites W2069514224 @default.
- W2012968596 cites W2072156178 @default.
- W2012968596 cites W2073229412 @default.
- W2012968596 cites W2073945839 @default.
- W2012968596 cites W2075159368 @default.
- W2012968596 cites W2076955078 @default.
- W2012968596 cites W2079024439 @default.
- W2012968596 cites W2080007643 @default.
- W2012968596 cites W2080630244 @default.
- W2012968596 cites W2084069906 @default.
- W2012968596 cites W2084233821 @default.
- W2012968596 cites W2084648582 @default.
- W2012968596 cites W2085155760 @default.
- W2012968596 cites W2091079643 @default.
- W2012968596 cites W2093187159 @default.
- W2012968596 cites W2093436341 @default.
- W2012968596 cites W2106448245 @default.
- W2012968596 cites W2169303193 @default.
- W2012968596 cites W2328624712 @default.
- W2012968596 cites W2951807258 @default.
- W2012968596 cites W2952231611 @default.
- W2012968596 cites W3005372756 @default.
- W2012968596 cites W4233025621 @default.
- W2012968596 cites W2082327913 @default.
- W2012968596 doi "https://doi.org/10.1016/s0968-0896(97)00051-5" @default.
- W2012968596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9222514" @default.
- W2012968596 hasPublicationYear "1997" @default.
- W2012968596 type Work @default.
- W2012968596 sameAs 2012968596 @default.
- W2012968596 citedByCount "75" @default.
- W2012968596 countsByYear W20129685962012 @default.
- W2012968596 countsByYear W20129685962014 @default.
- W2012968596 countsByYear W20129685962015 @default.
- W2012968596 countsByYear W20129685962016 @default.
- W2012968596 countsByYear W20129685962017 @default.
- W2012968596 countsByYear W20129685962018 @default.
- W2012968596 countsByYear W20129685962019 @default.
- W2012968596 countsByYear W20129685962020 @default.
- W2012968596 countsByYear W20129685962021 @default.
- W2012968596 countsByYear W20129685962022 @default.
- W2012968596 crossrefType "journal-article" @default.
- W2012968596 hasAuthorship W2012968596A5033744233 @default.
- W2012968596 hasAuthorship W2012968596A5066428999 @default.
- W2012968596 hasAuthorship W2012968596A5070599064 @default.
- W2012968596 hasConcept C104317684 @default.
- W2012968596 hasConcept C112887158 @default.
- W2012968596 hasConcept C145148216 @default.
- W2012968596 hasConcept C161790260 @default.
- W2012968596 hasConcept C178790620 @default.
- W2012968596 hasConcept C179303850 @default.
- W2012968596 hasConcept C181199279 @default.
- W2012968596 hasConcept C185592680 @default.
- W2012968596 hasConcept C21951064 @default.
- W2012968596 hasConcept C2777654166 @default.
- W2012968596 hasConcept C2779463914 @default.
- W2012968596 hasConcept C32909587 @default.
- W2012968596 hasConcept C34814092 @default.
- W2012968596 hasConcept C55493867 @default.