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- W2012981451 abstract "The effect of ascorbic acid 2-O-alpha-glucoside (AA-2G) on hydrocortisone (HC)-induced lens opacity in developing chick embryo was examined and compared with those of ascorbic acid (AsA) and ascorbic acid 2-phosphate (AA-2P). The opacity was dose-dependently inhibited by a single administration of 10 or 20 mumol/egg of AA-2G and by three repeated administrations of 1, 3 or 10 mumol/egg of AA-2G. AA-2G was the most effective among the three compounds. Glucose did not enhance the preventive effect of AsA against HC-induced opacity, and neither dehydro ascorbic acid nor glucose also prevented HC-induced cataract. In the histological study, we observed many small vacuoles in the nuclear region of the opaque lens treated with HC. AA-2G inhibited the formation of such vacuoles, an effect closely correlated with the prevention of cataract formation." @default.
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- W2012981451 date "1993-01-01" @default.
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- W2012981451 title "Effect of Ascorbic Acid 2-0-α-Glucoside on Hydrocortisone-Induced Cataract Formation in Developing Chick Embryos: I. Comparison of the Preventive Effect of Ascorbic Acid Derivatives" @default.
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- W2012981451 doi "https://doi.org/10.1089/jop.1993.9.59" @default.
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