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• W2013018052 abstract "Four novel quinonoid compounds are evaluated for their apoptotic potential against three cancer cell lines, i.e. MCF-7, HeLa and MG-63. APOPercentage™ assay was used for the screening of the compounds and it was established that the apoptotic potential of these compounds is cell line specific. The compound 2-(1′,4′-benzoquinon-2′-yl)-5-hydroxy-7-methyl-1,4-naphthoquinone (S4) was found to be most active, which has a potential to kill ∼99% of HeLa cancer cells in vitro after 72 h at a concentration of 10 μM. The compound’s ability to induce specific markers of apoptosis in HeLa cells is further confirmed by DNA fragmentation and cell cycle assays." @default.
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• W2013018052 date "2009-11-01" @default.
• W2013018052 modified "2023-09-23" @default.
• W2013018052 title "Pro-apoptotic activities of novel synthetic quinones in human cancer cell lines" @default.
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• W2013018052 doi "https://doi.org/10.1016/j.canlet.2009.04.036" @default.
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