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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013018983> ?p ?o ?g. }

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• W2013018983 abstract "A long-standing model postulates that X-chromosome dosage compensation in Drosophila occurs by twofold up-regulation of the single male X, but previous data cannot exclude an alternative model, in which male autosomes are down-regulated to balance gene expression. To distinguish between the two models, we used RNA interference to deplete Male-Specific Lethal (MSL) complexes from male-like tissue culture cells. We found that expression of many genes from the X chromosome decreased, while expression from the autosomes was largely unchanged. We conclude that the primary role of the MSL complex is to up-regulate the male X chromosome." @default.
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• W2013018983 date "2005-10-01" @default.
• W2013018983 modified "2023-10-09" @default.
• W2013018983 title "Global regulation of X chromosomal genes by the MSL complex in <i>Drosophila melanogaster</i>" @default.
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• W2013018983 doi "https://doi.org/10.1101/gad.1343705" @default.
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