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- W2013038081 abstract "Fungal peritonitis (FP) accounts for 3 - 6% of all peritonitis episodes in chronic peritoneal dialysis (PD), being associated with high morbidity and mortality. Mortality rates are in the range of 15 - 50%, and loss of the peritoneal membrane function can be over 40% (1). The most common cause of the disease is Candida species (C. albicans, C. parapsilosis, C. glabrata). Other yeasts and filamentous fungi such as Aspergillus, Paecilomyces, Penicillium, and Zygomycetes are found less frequently. The strongest risk factors for FP in PD patients are prolonged use of antibiotics and previous bacterial peritonitis (2). Other suggested risk factors are immunosuppression, malnutrition, bowel perforation, diverticulitis, and, possibly, certain comorbidities such as diabetes or neoplastic diseases (1).Paecilomyces spp is a filamentous fungus like the genus Penicillium and Aspergillus. It is found in soil and water and is one of the main dwellers of house dust. It is rarely associated with human infections. When a disease does occur, it is more often related to foreign bodies or immunosuppressed patients (3,4).After the earthquake of February 27, 2010, in Chile, there was an increase in the rate of FP from 1% to 6%, due to the appearance of 6 cases caused by Paecilomyces variotti (5).Here we describe the clinical characteristics and outcomes of 3 of these patients. Although there was no proof of the precise route of infection in our patients, in all 3 cases there was a major alteration in the storage of the PD fluid bags, resulting especially in exposure to excessive dust and destruction of the architecture of the storage holds. It is quite possible that in the context of a natural disaster like a big earthquake, the risk of infections associated with this fungus could increase because of the excessive dust in the environment." @default.
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- W2013038081 date "2014-05-01" @default.
- W2013038081 modified "2023-10-13" @default.
- W2013038081 title "Outbreak of Paecilomyces variotii Peritonitis in Peritoneal Dialysis Patients after the 2010 Chilean Earthquake" @default.
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- W2013038081 doi "https://doi.org/10.3747/pdi.2013.00157" @default.
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