Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013039650> ?p ?o ?g. }
- W2013039650 endingPage "141" @default.
- W2013039650 startingPage "135" @default.
- W2013039650 abstract "To summarize advances and limitations in pancreas procurement and preservation for pancreas and islet transplantation, and review advances in islet protection and preservation.Pancreases procured after cardiac death, with in-situ regional organ cooling, have been successfully used for islet transplantation. Colloid-free Celsior and histidine-tryptophan-ketoglutarate preservation solutions are comparable to University of Wisconsin solution when used for cold storage before pancreas transplantation. Colloid-free preservation solutions are inferior to University of Wisconsin solution for pancreas preservation prior to islet isolation and transplantation. Clinical reports on pancreas and islet transplants suggest that the two-layer method may not offer significant benefits over cold storage with the University of Wisconsin solution: improved oxygenation may depend on the graft size; benefits in experimental models may not translate to human organs. Improvements in islet yield and quality occurred from pancreases treated with inhibitors of stress-induced apoptosis during procurement, storage, isolation or culture. Pancreas perfusion may be desirable before islet isolation and transplantation and may improve islet yields and quality. Methods for real-time, noninvasive assessment of pancreas quality during preservation have been implemented and objective islet potency assays have been developed and validated. These innovations should contribute to objective evaluation and establishment of improved pancreas preservation and islet isolation strategies.Cold storage may be adequate for preservation before pancreas transplants, but insufficient when pancreases are processed for islets or when expanded donors are used. Supplementation of cold storage solutions with cytoprotective agents and perfusion may improve pancreas and islet transplant outcomes." @default.
- W2013039650 created "2016-06-24" @default.
- W2013039650 creator A5009329552 @default.
- W2013039650 creator A5030109410 @default.
- W2013039650 creator A5031755211 @default.
- W2013039650 creator A5044504337 @default.
- W2013039650 date "2008-04-01" @default.
- W2013039650 modified "2023-10-07" @default.
- W2013039650 title "Pancreas preservation for pancreas and islet transplantation" @default.
- W2013039650 cites W1586395264 @default.
- W2013039650 cites W1964637135 @default.
- W2013039650 cites W1966051569 @default.
- W2013039650 cites W1967816717 @default.
- W2013039650 cites W1974730182 @default.
- W2013039650 cites W1975098856 @default.
- W2013039650 cites W1978815496 @default.
- W2013039650 cites W1981310806 @default.
- W2013039650 cites W1981432917 @default.
- W2013039650 cites W1982918561 @default.
- W2013039650 cites W1987069546 @default.
- W2013039650 cites W1987947487 @default.
- W2013039650 cites W1988025757 @default.
- W2013039650 cites W1992623347 @default.
- W2013039650 cites W1994428602 @default.
- W2013039650 cites W1995893959 @default.
- W2013039650 cites W1997731726 @default.
- W2013039650 cites W2002075796 @default.
- W2013039650 cites W2002351860 @default.
- W2013039650 cites W2005011354 @default.
- W2013039650 cites W2006919788 @default.
- W2013039650 cites W2011525185 @default.
- W2013039650 cites W2017140956 @default.
- W2013039650 cites W2018660174 @default.
- W2013039650 cites W2021646109 @default.
- W2013039650 cites W2027967953 @default.
- W2013039650 cites W2029307475 @default.
- W2013039650 cites W2031021185 @default.
- W2013039650 cites W2035670961 @default.
- W2013039650 cites W2042254298 @default.
- W2013039650 cites W2044669680 @default.
- W2013039650 cites W2048908986 @default.
- W2013039650 cites W2054623041 @default.
- W2013039650 cites W2056868130 @default.
- W2013039650 cites W2061273411 @default.
- W2013039650 cites W2061902823 @default.
- W2013039650 cites W2062536259 @default.
- W2013039650 cites W2062576688 @default.
- W2013039650 cites W2064517350 @default.
- W2013039650 cites W2066354143 @default.
- W2013039650 cites W2068622774 @default.
- W2013039650 cites W2070078940 @default.
- W2013039650 cites W2070444065 @default.
- W2013039650 cites W2072704470 @default.
- W2013039650 cites W2075054744 @default.
- W2013039650 cites W2079144094 @default.
- W2013039650 cites W2083972634 @default.
- W2013039650 cites W2084774780 @default.
- W2013039650 cites W2089237784 @default.
- W2013039650 cites W2095446401 @default.
- W2013039650 cites W2095588097 @default.
- W2013039650 cites W2096231880 @default.
- W2013039650 cites W2101820691 @default.
- W2013039650 cites W2103110619 @default.
- W2013039650 cites W2108040825 @default.
- W2013039650 cites W2108380410 @default.
- W2013039650 cites W2109832090 @default.
- W2013039650 cites W2117129841 @default.
- W2013039650 cites W2120811858 @default.
- W2013039650 cites W2154765637 @default.
- W2013039650 cites W2160885748 @default.
- W2013039650 cites W2169335085 @default.
- W2013039650 cites W2171274341 @default.
- W2013039650 cites W274927353 @default.
- W2013039650 cites W4237974384 @default.
- W2013039650 cites W4239472340 @default.
- W2013039650 cites W4240570529 @default.
- W2013039650 cites W4255458528 @default.
- W2013039650 doi "https://doi.org/10.1097/mot.0b013e3282f63942" @default.
- W2013039650 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2858000" @default.
- W2013039650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18685343" @default.
- W2013039650 hasPublicationYear "2008" @default.
- W2013039650 type Work @default.
- W2013039650 sameAs 2013039650 @default.
- W2013039650 citedByCount "37" @default.
- W2013039650 countsByYear W20130396502012 @default.
- W2013039650 countsByYear W20130396502013 @default.
- W2013039650 countsByYear W20130396502014 @default.
- W2013039650 countsByYear W20130396502015 @default.
- W2013039650 countsByYear W20130396502016 @default.
- W2013039650 countsByYear W20130396502017 @default.
- W2013039650 countsByYear W20130396502018 @default.
- W2013039650 countsByYear W20130396502019 @default.
- W2013039650 countsByYear W20130396502022 @default.
- W2013039650 countsByYear W20130396502023 @default.
- W2013039650 crossrefType "journal-article" @default.
- W2013039650 hasAuthorship W2013039650A5009329552 @default.
- W2013039650 hasAuthorship W2013039650A5030109410 @default.
- W2013039650 hasAuthorship W2013039650A5031755211 @default.