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• W2013048124 abstract "In studying the mechanism of tRNA adaptation to silk fibroin and sericin mRNA translation, we investigated the accumulation rates of tRNA species rapidly labeled in vivo in the posterior and middle silk glands of the silkworm Bombyx mori during the last larval instar. We found that the rates of synthesis of total and individual tRNA species labeled with [3H]uridine during the growth and the secretion phases and separated by electrophoresis on polyacrylamide gels, are specific for each tRNA species and each tissue. We noted continuous variations of the tRNA levels designed to reflect changes in the population of mRNAs. The tRNA adaptation to silk mRNAs is completed roughly at the end of the growth phase and at the beginning of the secretion phase (day four of the Vth instar). Its stabilization during the secretion phase occurs by a reversal of the relative rates of predominant tRNA species, mainly tRNAGly. The sum total of the synthetic rates for each tRNA species corroborates their known adaptive distribution during the secretion phase of silk proteins. In addition, when coupled to the similarity of their turnover rates, observed previously, the data support a transcriptional control of tRNA genes." @default.
• W2013048124 created "2016-06-24" @default.
• W2013048124 creator A5039603921 @default.
• W2013048124 creator A5048637308 @default.
• W2013048124 date "2005-03-03" @default.
• W2013048124 modified "2023-10-16" @default.
• W2013048124 title "Differential Synthesis Rates of tRNA Species in the Silk Gland of Bombyx mori Are Required to Promote tRNA Adaptation to Silk Messages" @default.
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• W2013048124 doi "https://doi.org/10.1111/j.1432-1033.1982.tb06618.x" @default.
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