Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013059458> ?p ?o ?g. }
- W2013059458 endingPage "1350027" @default.
- W2013059458 startingPage "1350027" @default.
- W2013059458 abstract "The mechanism of action of vagus nerve stimulation (VNS) for pharmacoresistant epilepsy is unknown and the therapeutic outcome is highly variable. We investigated stimulation-induced vagus nerve electrophysiological responses in rats using various stimulation parameters. Conduction velocity, I 50 , rheobase and chronaxie were calculated. We identified an early and late component corresponding to an afferent compound action potential (CAP) and a remote laryngeal motor-evoked potential (LMEP), respectively. The conduction velocity (CAP: 26.2 ± 1.4 m/s; LMEP: 32.4 ± 2.4 m/s) and I 50 (CAP: 2.4 ± 0.3 mA; LMEP: 1.8±0.2 mA) were significantly different for both components, the rheobase (CAP: 140±30 μA; LMEP: 110±26 μA) and chronaxie (CAP: 66±7 μs; LMEP: 73±9 μs) were not. Using a pulse of 10 μs, the CAP saturated between 4–5 mA. Our method can be used to record VNS-induced electrophysiological responses in rats and provides an objective biomarker for electrical stimulation with various parameters in an experimental set-up. Our findings are potentially useful for clinical purposes in the sense that combination of VNS and recording of vagal nerve CAPs may help clinicians to determine the individual optimal intensity required to fully activate fast-conducting afferent fibers." @default.
- W2013059458 created "2016-06-24" @default.
- W2013059458 creator A5005404511 @default.
- W2013059458 creator A5006345103 @default.
- W2013059458 creator A5009531136 @default.
- W2013059458 creator A5029948503 @default.
- W2013059458 creator A5031094049 @default.
- W2013059458 creator A5035157889 @default.
- W2013059458 creator A5039470804 @default.
- W2013059458 creator A5057508554 @default.
- W2013059458 creator A5058815082 @default.
- W2013059458 creator A5068812217 @default.
- W2013059458 creator A5087755849 @default.
- W2013059458 date "2013-10-25" @default.
- W2013059458 modified "2023-10-16" @default.
- W2013059458 title "ELECTROPHYSIOLOGICAL RESPONSES FROM VAGUS NERVE STIMULATION IN RATS" @default.
- W2013059458 cites W1963666492 @default.
- W2013059458 cites W1969188156 @default.
- W2013059458 cites W1971482087 @default.
- W2013059458 cites W1971517399 @default.
- W2013059458 cites W1977774641 @default.
- W2013059458 cites W1979937204 @default.
- W2013059458 cites W1980606251 @default.
- W2013059458 cites W1981476129 @default.
- W2013059458 cites W1990274030 @default.
- W2013059458 cites W2000891462 @default.
- W2013059458 cites W2001944673 @default.
- W2013059458 cites W2004581037 @default.
- W2013059458 cites W2005491259 @default.
- W2013059458 cites W2006689666 @default.
- W2013059458 cites W2011163101 @default.
- W2013059458 cites W2011248940 @default.
- W2013059458 cites W2015202629 @default.
- W2013059458 cites W2017734759 @default.
- W2013059458 cites W2022305238 @default.
- W2013059458 cites W2038561889 @default.
- W2013059458 cites W2038954900 @default.
- W2013059458 cites W2039774874 @default.
- W2013059458 cites W2050271537 @default.
- W2013059458 cites W2059355906 @default.
- W2013059458 cites W2066366977 @default.
- W2013059458 cites W2078135788 @default.
- W2013059458 cites W2078790407 @default.
- W2013059458 cites W2079487783 @default.
- W2013059458 cites W2085756185 @default.
- W2013059458 cites W2086084057 @default.
- W2013059458 cites W2098647834 @default.
- W2013059458 cites W2104654650 @default.
- W2013059458 cites W2110911785 @default.
- W2013059458 cites W2114427832 @default.
- W2013059458 cites W2114638688 @default.
- W2013059458 cites W2142295683 @default.
- W2013059458 cites W2145055084 @default.
- W2013059458 cites W2150793389 @default.
- W2013059458 cites W2151048657 @default.
- W2013059458 cites W2154557118 @default.
- W2013059458 cites W2166635848 @default.
- W2013059458 cites W2168717107 @default.
- W2013059458 cites W2329237037 @default.
- W2013059458 cites W2569047360 @default.
- W2013059458 cites W4292167789 @default.
- W2013059458 doi "https://doi.org/10.1142/s0129065713500275" @default.
- W2013059458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24156670" @default.
- W2013059458 hasPublicationYear "2013" @default.
- W2013059458 type Work @default.
- W2013059458 sameAs 2013059458 @default.
- W2013059458 citedByCount "26" @default.
- W2013059458 countsByYear W20130594582015 @default.
- W2013059458 countsByYear W20130594582016 @default.
- W2013059458 countsByYear W20130594582017 @default.
- W2013059458 countsByYear W20130594582018 @default.
- W2013059458 countsByYear W20130594582019 @default.
- W2013059458 countsByYear W20130594582020 @default.
- W2013059458 countsByYear W20130594582022 @default.
- W2013059458 countsByYear W20130594582023 @default.
- W2013059458 crossrefType "journal-article" @default.
- W2013059458 hasAuthorship W2013059458A5005404511 @default.
- W2013059458 hasAuthorship W2013059458A5006345103 @default.
- W2013059458 hasAuthorship W2013059458A5009531136 @default.
- W2013059458 hasAuthorship W2013059458A5029948503 @default.
- W2013059458 hasAuthorship W2013059458A5031094049 @default.
- W2013059458 hasAuthorship W2013059458A5035157889 @default.
- W2013059458 hasAuthorship W2013059458A5039470804 @default.
- W2013059458 hasAuthorship W2013059458A5057508554 @default.
- W2013059458 hasAuthorship W2013059458A5058815082 @default.
- W2013059458 hasAuthorship W2013059458A5068812217 @default.
- W2013059458 hasAuthorship W2013059458A5087755849 @default.
- W2013059458 hasConcept C126322002 @default.
- W2013059458 hasConcept C151626666 @default.
- W2013059458 hasConcept C169760540 @default.
- W2013059458 hasConcept C179253579 @default.
- W2013059458 hasConcept C185263204 @default.
- W2013059458 hasConcept C185592680 @default.
- W2013059458 hasConcept C24998067 @default.
- W2013059458 hasConcept C2780087125 @default.
- W2013059458 hasConcept C2781404750 @default.
- W2013059458 hasConcept C42219234 @default.
- W2013059458 hasConcept C71924100 @default.