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- W2013060059 abstract "Abstract Specimens from eight patients with buccal leukoplakia (hyperkeratosis) were studied for ultrastructural localization of acid phosphatase. Biopsies were obtained from both the leukoplakic lesion and adjacent normal-appearing mucosa in each patient. Intra and extracellular acid phosphatase activity was found in both normal and leukoplakic epithelium. The greatest concentrations occurred in the surface of unkeratinized epithelium and in the granular and low surface strata of keratinized epithelium. Intracellular activity was localized in the Golgi complex, endoplasmic reticulum and a variety of lysosomal bodies. Observations suggested a Golgi complex and endoplasmic reticulum origin of acid phosphatase with distribution in lysosomal dense bodies, microgranules, autophagic vacuoles, multivesicular bodies and residual bodies. Intercellular activity occurred as clumps and as homogeneous or striated plaques of material which appeared to be derived partly from microgranules. There was a greater amount of reaction product in leukoplakic specimens, indicating a possible role of lysosomes in keratinization." @default.
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- W2013060059 title "Ultrastructural localization of acid phosphatase in human buccal epithelium" @default.
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- W2013060059 doi "https://doi.org/10.1016/0003-9969(70)90051-8" @default.
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