FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013083146> ?p ?o ?g. }

• W2013083146 endingPage "128" @default.
• W2013083146 startingPage "119" @default.
• W2013083146 abstract "Toll-like receptor 2 (TLR2) is a member of an ancient pattern recognition receptor family, conserved from insects to mammals and it is best known as a receptor for recognizing conserved components of Gram-positive bacteria. In present study, the genomic structure of TLR2 gene from miiuy croaker was identified and characterized. It comprises twelve exons and eleven introns. The lengths of exons 3 to 10 of miiuy croaker TLR2 and exons 2 to 9 of fugu and pufferfish TLR2 are exactly the same, but most importantly, both of fugu and pufferfish have only eleven exons and ten introns. An intron insert event probably happened on exon 1 of miiuy croaker TLR2 after its divergence from ancestor of zebrafish, and an intron loss event probably happened on those of Tetraodontiformes TLR2 after the divergence with ancestor of miiuy croaker. Our study showed the direct evidence and strongly supported the intron insert and loss on fish TLR2. The pathogen injection experiments indicated that TLR2 might not be an important responder to Gram-negative bacteria in miiuy croaker. Molecular evolutionary analyses indicated TLR2 genes were under strong purifying selection pressure, showing a quite strong functional constraint in both of fish and mammals, despite of their distinct living environment conditions." @default.
• W2013083146 created "2016-06-24" @default.
• W2013083146 creator A5007982250 @default.
• W2013083146 creator A5019373327 @default.
• W2013083146 creator A5077170267 @default.
• W2013083146 creator A5087791435 @default.
• W2013083146 date "2013-01-01" @default.
• W2013083146 modified "2023-10-14" @default.
• W2013083146 title "Characterization and comprehensive analysis of the miiuy croaker TLR2 reveals a direct evidence for intron insert and loss" @default.
• W2013083146 cites W1483896507 @default.
• W2013083146 cites W1514540900 @default.
• W2013083146 cites W1650179436 @default.
• W2013083146 cites W1767163685 @default.
• W2013083146 cites W1968134126 @default.
• W2013083146 cites W1969072247 @default.
• W2013083146 cites W1972776583 @default.
• W2013083146 cites W1977922844 @default.
• W2013083146 cites W1978962348 @default.
• W2013083146 cites W1991236592 @default.
• W2013083146 cites W2001873744 @default.
• W2013083146 cites W2002747155 @default.
• W2013083146 cites W2004773897 @default.
• W2013083146 cites W2008116827 @default.
• W2013083146 cites W2008152503 @default.
• W2013083146 cites W2016862474 @default.
• W2013083146 cites W2041631230 @default.
• W2013083146 cites W2043623544 @default.
• W2013083146 cites W2054841888 @default.
• W2013083146 cites W2055773854 @default.
• W2013083146 cites W2056649461 @default.
• W2013083146 cites W2062295899 @default.
• W2013083146 cites W2067461984 @default.
• W2013083146 cites W2069696438 @default.
• W2013083146 cites W2076361525 @default.
• W2013083146 cites W2078664576 @default.
• W2013083146 cites W2079605309 @default.
• W2013083146 cites W2080667183 @default.
• W2013083146 cites W2087368694 @default.
• W2013083146 cites W2089002446 @default.
• W2013083146 cites W2089047063 @default.
• W2013083146 cites W2097098907 @default.
• W2013083146 cites W2097382368 @default.
• W2013083146 cites W2101363646 @default.
• W2013083146 cites W2107277218 @default.
• W2013083146 cites W2110335151 @default.
• W2013083146 cites W2111260918 @default.
• W2013083146 cites W2112176050 @default.
• W2013083146 cites W2120611093 @default.
• W2013083146 cites W2125121305 @default.
• W2013083146 cites W2132886879 @default.
• W2013083146 cites W2136021653 @default.
• W2013083146 cites W2146058063 @default.
• W2013083146 cites W2152506689 @default.
• W2013083146 cites W2154239819 @default.
• W2013083146 cites W2157339124 @default.
• W2013083146 cites W2166187656 @default.
• W2013083146 doi "https://doi.org/10.1016/j.fsi.2012.10.008" @default.
• W2013083146 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23069786" @default.
• W2013083146 hasPublicationYear "2013" @default.
• W2013083146 type Work @default.
• W2013083146 sameAs 2013083146 @default.
• W2013083146 citedByCount "19" @default.
• W2013083146 countsByYear W20130831462015 @default.
• W2013083146 countsByYear W20130831462016 @default.
• W2013083146 countsByYear W20130831462017 @default.
• W2013083146 countsByYear W20130831462018 @default.
• W2013083146 countsByYear W20130831462019 @default.
• W2013083146 countsByYear W20130831462020 @default.
• W2013083146 countsByYear W20130831462021 @default.
• W2013083146 countsByYear W20130831462022 @default.
• W2013083146 crossrefType "journal-article" @default.
• W2013083146 hasAuthorship W2013083146A5007982250 @default.
• W2013083146 hasAuthorship W2013083146A5019373327 @default.
• W2013083146 hasAuthorship W2013083146A5077170267 @default.
• W2013083146 hasAuthorship W2013083146A5087791435 @default.
• W2013083146 hasConcept C104317684 @default.
• W2013083146 hasConcept C141231307 @default.
• W2013083146 hasConcept C156446351 @default.
• W2013083146 hasConcept C193252679 @default.
• W2013083146 hasConcept C2778873838 @default.
• W2013083146 hasConcept C36823959 @default.
• W2013083146 hasConcept C54355233 @default.
• W2013083146 hasConcept C78458016 @default.
• W2013083146 hasConcept C86803240 @default.
• W2013083146 hasConcept C94671646 @default.
• W2013083146 hasConceptScore W2013083146C104317684 @default.
• W2013083146 hasConceptScore W2013083146C141231307 @default.
• W2013083146 hasConceptScore W2013083146C156446351 @default.
• W2013083146 hasConceptScore W2013083146C193252679 @default.
• W2013083146 hasConceptScore W2013083146C2778873838 @default.
• W2013083146 hasConceptScore W2013083146C36823959 @default.
• W2013083146 hasConceptScore W2013083146C54355233 @default.
• W2013083146 hasConceptScore W2013083146C78458016 @default.
• W2013083146 hasConceptScore W2013083146C86803240 @default.
• W2013083146 hasConceptScore W2013083146C94671646 @default.
• W2013083146 hasIssue "1" @default.
• W2013083146 hasLocation W20130831461 @default.
• W2013083146 hasLocation W20130831462 @default.

• next