FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2013092934> ?p ?o ?g. }

• W2013092934 endingPage "179" @default.
• W2013092934 startingPage "173" @default.
• W2013092934 abstract "Mammalian cells have evolved elaborate mechanisms for protection against the toxic and neoplastic effects of electrophilic metabolites of carcinogens and reactive oxygen species. Phase 2 enzymes (e.g. glutathione transferase, NAD(P)H:quinone reductase, UDP-glucuronosyltransferases) and high intracellular levels of glutathione play a prominent role in providing such protection. Phase 2 enzymes are transcriptionally induced by low concentrations of a wide variety of chemical agents and such induction blocks chemical carcinogenesis. The inducers belong to many chemical classes including phenolic antioxidants, Michael reaction acceptors, isothiocyanates, 1,2-dithiole-3-thiones, trivalent arsenicals, HgCl2 and organomercurials, hydroperoxides, and vicinal dimercaptans. Induction by all classes of inducers involves the antioxidant/electrophile response element (ARE/EpRE). Inducers are widely, but unequally, distributed among edible plants. Search for such inducer activity in broccoli led to the isolation of sulforaphane, an isothiocyanate that is a very potent Phase 2 enzyme inducer and blocks mammary tumor formation in rats." @default.
• W2013092934 created "2016-06-24" @default.
• W2013092934 creator A5011065831 @default.
• W2013092934 creator A5013304534 @default.
• W2013092934 creator A5048525964 @default.
• W2013092934 creator A5050503238 @default.
• W2013092934 creator A5073144179 @default.
• W2013092934 date "1995-12-01" @default.
• W2013092934 modified "2023-09-23" @default.
• W2013092934 title "Chemoprotection against cancer by Phase 2 enzyme induction" @default.
• W2013092934 cites W1561096292 @default.
• W2013092934 cites W1604748982 @default.
• W2013092934 cites W1652134433 @default.
• W2013092934 cites W1858268805 @default.
• W2013092934 cites W1972441677 @default.
• W2013092934 cites W1974100862 @default.
• W2013092934 cites W1975512386 @default.
• W2013092934 cites W1982628675 @default.
• W2013092934 cites W1985385055 @default.
• W2013092934 cites W1997506075 @default.
• W2013092934 cites W2002667886 @default.
• W2013092934 cites W2005644558 @default.
• W2013092934 cites W2005961230 @default.
• W2013092934 cites W2008150054 @default.
• W2013092934 cites W2024289938 @default.
• W2013092934 cites W2045061052 @default.
• W2013092934 cites W2062318132 @default.
• W2013092934 cites W2076429988 @default.
• W2013092934 cites W263107808 @default.
• W2013092934 doi "https://doi.org/10.1016/0378-4274(95)03553-2" @default.
• W2013092934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8597048" @default.
• W2013092934 hasPublicationYear "1995" @default.
• W2013092934 type Work @default.
• W2013092934 sameAs 2013092934 @default.
• W2013092934 citedByCount "416" @default.
• W2013092934 countsByYear W20130929342012 @default.
• W2013092934 countsByYear W20130929342013 @default.
• W2013092934 countsByYear W20130929342014 @default.
• W2013092934 countsByYear W20130929342015 @default.
• W2013092934 countsByYear W20130929342016 @default.
• W2013092934 countsByYear W20130929342017 @default.
• W2013092934 countsByYear W20130929342018 @default.
• W2013092934 countsByYear W20130929342019 @default.
• W2013092934 countsByYear W20130929342020 @default.
• W2013092934 countsByYear W20130929342021 @default.
• W2013092934 countsByYear W20130929342022 @default.
• W2013092934 countsByYear W20130929342023 @default.
• W2013092934 crossrefType "journal-article" @default.
• W2013092934 hasAuthorship W2013092934A5011065831 @default.
• W2013092934 hasAuthorship W2013092934A5013304534 @default.
• W2013092934 hasAuthorship W2013092934A5048525964 @default.
• W2013092934 hasAuthorship W2013092934A5050503238 @default.
• W2013092934 hasAuthorship W2013092934A5073144179 @default.
• W2013092934 hasBestOaLocation W20130929341 @default.
• W2013092934 hasConcept C104317684 @default.
• W2013092934 hasConcept C114246631 @default.
• W2013092934 hasConcept C132154277 @default.
• W2013092934 hasConcept C134651460 @default.
• W2013092934 hasConcept C165069038 @default.
• W2013092934 hasConcept C181199279 @default.
• W2013092934 hasConcept C185592680 @default.
• W2013092934 hasConcept C2225953 @default.
• W2013092934 hasConcept C2777476445 @default.
• W2013092934 hasConcept C2778760513 @default.
• W2013092934 hasConcept C2780841255 @default.
• W2013092934 hasConcept C538909803 @default.
• W2013092934 hasConcept C55493867 @default.
• W2013092934 hasConcept C75520062 @default.
• W2013092934 hasConceptScore W2013092934C104317684 @default.
• W2013092934 hasConceptScore W2013092934C114246631 @default.
• W2013092934 hasConceptScore W2013092934C132154277 @default.
• W2013092934 hasConceptScore W2013092934C134651460 @default.
• W2013092934 hasConceptScore W2013092934C165069038 @default.
• W2013092934 hasConceptScore W2013092934C181199279 @default.
• W2013092934 hasConceptScore W2013092934C185592680 @default.
• W2013092934 hasConceptScore W2013092934C2225953 @default.
• W2013092934 hasConceptScore W2013092934C2777476445 @default.
• W2013092934 hasConceptScore W2013092934C2778760513 @default.
• W2013092934 hasConceptScore W2013092934C2780841255 @default.
• W2013092934 hasConceptScore W2013092934C538909803 @default.
• W2013092934 hasConceptScore W2013092934C55493867 @default.
• W2013092934 hasConceptScore W2013092934C75520062 @default.
• W2013092934 hasLocation W20130929341 @default.
• W2013092934 hasLocation W20130929342 @default.
• W2013092934 hasOpenAccess W2013092934 @default.
• W2013092934 hasPrimaryLocation W20130929341 @default.
• W2013092934 hasRelatedWork W1965046058 @default.
• W2013092934 hasRelatedWork W1967077010 @default.
• W2013092934 hasRelatedWork W1997196963 @default.
• W2013092934 hasRelatedWork W2048243780 @default.
• W2013092934 hasRelatedWork W2461803461 @default.
• W2013092934 hasRelatedWork W2503181728 @default.
• W2013092934 hasRelatedWork W264219250 @default.
• W2013092934 hasRelatedWork W3154365496 @default.
• W2013092934 hasRelatedWork W4233427342 @default.
• W2013092934 hasRelatedWork W790312177 @default.
• W2013092934 hasVolume "82-83" @default.
• W2013092934 isParatext "false" @default.

• next